Caffeine Consumption and Mortality in Diabetes: An Analysis of NHANES 1999-2010
Neves JS, Leitão L, Magriço R, Bigotte Vieira M, Viegas Dias C, Oliveira A, Carvalho D, Claggett B
Frontiers in endocrinology · 35 citas
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Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2018-09-20 · Front Endocrinol (Lausanne) · vol. 9 · pág. 547
- Editorial
- Frontiers Media
- Citado
- 43 citas · más que el 85% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 31 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Coffee research and impacts · Obesity, Physical Activity, Diet · Nutritional Studies and Diet
- Palabras clave
- Caffeine, Medicine, National Health and Nutrition Examination Survey, Hazard ratio, Confounding, Diabetes mellitus, Proportional hazards model, Population, Internal medicine, Demography, Environmental health, Physiology, Confidence interval, Endocrinology
8 autores
- João Sérgio Neves🇵🇹 · autor de correspondenciaUniversidade do Porto; Hospital de São João
- Lia Leitão🇵🇹Hospital Prof. Dr. Fernando Fonseca
- Rita Magriço🇵🇹Hospital Curry Cabral
- Miguel Bigotte Vieira🇵🇹Centro Hospitalar Lisboa Norte
- Catarina Viegas Dias🇵🇹Universidade Nova de Lisboa
- Ana Beatriz Furtado De Oliveira🇵🇹Hospital de São João
- Davide Maurício Carvalho🇵🇹Hospital de São João; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
- Brian Lee Claggett🇺🇸Brigham and Women's Hospital; Harvard University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim: An inverse relationship between coffee consumption and mortality has been reported in the general population. However, the effect of coffee consumption in diabetes remains unclear. We aimed to evaluate the association of caffeine consumption and caffeine source with mortality among patients with diabetes. Methods: We examined the association of caffeine consumption with mortality among 1974 women and 1974 men with diabetes, using the National Health and Nutrition Examination Survey (NHANES) 1999-2010. Caffeine consumption was assessed at baseline using 24 h dietary recalls. Cox proportional hazard models were fitted to estimate hazard ratios (HR) for all-cause, cardiovascular, and cancer-related mortality according to caffeine consumption and its source, adjusting for potential confounders. Results: A dose-dependent inverse association between caffeine and all-cause mortality was observed in women with diabetes. Adjusted HR for death among women who consumed caffeine, as compared with non-consumers, were: 0.57 (95% CI, 0.40-0.82) for p = 0.005 for trend). This association was not observed in men. There was a significant interaction between sex and caffeine consumption (p = 0.015). No significant association between total caffeine consumption and cardiovascular or cancer mortality was observed. Women who consumed more caffeine from coffee had reduced risk of all-cause mortality (p = 0.004 for trend). Conclusion: Our study showed a dose-dependent protective effect of caffeine consumption on mortality among women with diabetes.
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