The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials
Tabrizi R, Saneei P, Lankarani KB, Akbari M, Kolahdooz F, Esmaillzadeh A, Nadi-Ravandi S, Mazoochi M, Asemi Z
Critical reviews in food science and nutrition · 77 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Shiraz University of Medical Sciences
Según 1 financiador declarado.
Publicación
- Publicado
- 2018-10-18 · Crit Rev Food Sci Nutr · vol. 59 · número 16 · págs. 2688–2696
- Editorial
- Taylor & Francis
- Citado
- 122 citas · más que el 60% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Diet and metabolism studies · Eating Disorders and Behaviors
- Palabras clave
- Meta-analysis, Randomized controlled trial, Weight loss, Caffeine, Medicine, Food science, Internal medicine, Biology, Obesity
- MeSH
- humans, weight loss, caffeine, central nervous system stimulants, dose-response relationship, drug
9 autores
- Reza Tabrizi🇮🇷Shiraz University of Medical Sciences
- Parvane Saneei🇮🇷Isfahan University of Medical Sciences
- Kamran Bagheri Lankarani🇮🇷Shiraz University of Medical Sciences
- Maryam Akbari🇮🇷Shiraz University of Medical Sciences
- Fariba Kolahdooz🇨🇦University of Alberta
- Ahmad Esmaillzadeh🇮🇷Isfahan University of Medical Sciences; Tehran University of Medical Sciences
- Somayyeh Nadi-Ravandi🇮🇷Kashan University of Medical Sciences
- Majid Mazoochi🇮🇷Kashan University of Medical Sciences
- Zatollah Asemi🇮🇷 · autor de correspondenciaKashan University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
This systematic review and meta-analysis of randomized controlled trials (RCTs) was performed to summarize the effect of caffeine intake on weight loss. We searched the following databases until November 2017: MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials. The relevant data were extracted and assessed for quality of the studies according to the Cochrane risk of bias tool. We estimated an intake-status regression coefficient (Beta) for each primary study and estimated the overall pooled Beta and SE using random effects meta-analysis on a double-log scale. Heterogeneity between studies was assessed by the Cochran Q statistic and I-squared tests (I2). Thirteen RCTs with 606 participants were included in the meta-analyses. The overall pooled Beta for the effect of caffeine intake was 0.29 (95%CI: 0.19, 0.40; Q = 124.5, I2 = 91.2%) for weigh, 0.23 (95%CI: 0.09, 0.36; Q = 71.0, I2 = 93.0%) for BMI, and 0.36 (95% CI: 0.24, 0.48; Q = 167.36, I2 = 94.0%) for fat mass. For every doubling in caffeine intake, the mean reduction in weight, BMI, and fat mass increased 2 Beta-fold (20.29 = 1.22, 20.23 = 1.17, and 20.36 = 1.28), which corresponding to 22, 17, and 28 percent, respectively. Overall, the current meta-analysis demonstrated that caffeine intake might promote weight, BMI and body fat reduction.
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