Financiado en parte por Amgen, AstraZeneca, Sanofi
A higher ratio of refined grain to whole grain is associated with a greater likelihood of chronic kidney disease: a population-based study
Mazidi M, Katsiki N, Mikhailidis DP, Banach M
The British journal of nutrition · 17 citas
Etiquetas de revisión
Financiado por la industriaSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- Amgen
- Empresa
- AstraZeneca
- Empresa
- Sanofi
Según 3 financiadores declarados.
Publicación
- Publicado
- 2018-10-30 · Br J Nutr · vol. 121 · número 11 · págs. 1294–1302
- Editorial
- Cambridge University Press
- Citado
- 22 citas · más que el 69% de estudios similares · 0.7× el promedio de su campo
- Referencias
- 66 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Food composition and properties · Nutritional Studies and Diet · Nutrition and Health in Aging
- Palabras clave
- Kidney disease, Population, Disease, Medicine, Biology, Animal science, Internal medicine, Environmental health
- MeSH
- humans, albuminuria, creatinine, uric acid, albumins, kidney function tests, glomerular filtration rate, diet, nutrition surveys, prevalence, logistic models, risk factors, cross-sectional studies, adult, aged, middle aged, female, male, renal insufficiency, chronic, edible grain, whole grains
4 autores
- Mohsen Mazidi🇨🇳 · autor de correspondenciaChinese Academy of Sciences; Institute of Genetics and Developmental Biology
- Niki Katsiki🇬🇷Aristotle University of Thessaloniki; Ippokrateio General Hospital of Thessaloniki
- Dimitri P. Mikhailidis🇬🇧The Royal Free Hospital; University College London
- Maciej Banach🇵🇱Medical University of Lodz; Polish Mother’s Memorial Hospital Research Institute; University of Zielona Góra
Resumen
El texto original del estudio, en el idioma en que se publicó.
A growing number of studies suggest that diet and renal function are related. However, little is known about the link between both whole grain (WG) and refined grain (RG) consumption and kidney function parameters. Thus, we investigated the association of WG and RG with urinary albumin to creatinine ratio (ACR) and prevalent chronic kidney disease (CKD). Data from participants of the National Health and Nutrition Examination Surveys (NHANES) from 2005 to 2010 were collected. Estimated glomerular filtration rate (eGFR) was calculated by the CKD Epidemiology Collaboration equation. Survey design and sample weights were taken into consideration for statistical analyses. Finally, we included 16 325 participants from NHANES, 6·9 % of whom had prevalent CKD. In models adjusted for age, sex, race, fasting blood glucose, blood pressure, adiposity, hypertension and diabetes status, mean eGFR significantly increased across increasing quartiles of WG (Q1: 88·2 v. Q4: 95·4 ml/min per 1·73 m2, P<0·001), whereas it significantly decreased across increasing quartiles of RG (Q1: 97·2 v. Q4: 88·4 ml/min per 1·73 m2, P<0·001). Furthermore, serum uric acid levels and ACR significantly decreased across quartiles of WG (both P<0·001). In multivariable-adjusted logistic regression models, the likelihood of prevalent CKD was 21 % lower in the highest WG quartile compared with the lowest one. In conclusion, our results shed light on the beneficial impact of WG on kidney function and CKD, whereas RG is adversely associated with eGFR.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.