Effects of cholecalciferol supplementation on inflammatory markers and muscle damage indices of soccer players after a simulated soccer match
Parsaie N, Ghavamzadeh S, Cheraghi M
Nutrition (Burbank, Los Angeles County, Calif.) · 8 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2018-07-14 · Nutrition · vol. 59 · págs. 37–43
- Editorial
- Elsevier BV
- Citado
- 13 citas · más que el 68% de estudios similares · 0.5× el promedio de su campo
- Referencias
- 71 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-ND
- Áreas de investigación
- Exercise and Physiological Responses · Vitamin D Research Studies · Pharmacological Effects and Assays
- Palabras clave
- Cholecalciferol, Placebo, Vitamin D and neurology, Medicine, Internal medicine, Creatine kinase, Endocrinology, Vitamin, Interquartile range, Inflammation, Pathology
- MeSH
- muscle, skeletal, humans, inflammation, cholecalciferol, vitamins, vitamin d, inflammation mediators, body mass index, double-blind method, oxygen consumption, soccer, dietary supplements, computer simulation, adult, male, athletic performance, young adult, biomarkers
3 autores
- Narges Parsaie🇮🇷Urmia University; Urmia University of Medical Sciences
- Saeed Ghavamzadeh🇮🇷 · autor de correspondenciaUrmia University; Urmia University of Medical Sciences
- Mahdi Cheraghi
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
Soccer-induced muscle damage and inflammation lead to a reduction in athletic performance. The aim of this study was to determine whether supplementation with cholecalciferol would reduce inflammation and muscle damage in soccer players after a simulated soccer match.
Methods
Twenty-two soccer players (median age 27 y, interquartile range 5 y) were divided randomly into two groups, as follows: a cholecalciferol group (n = 11) and a placebo group (n = 11). Cholecalciferol supplements (50 000 IU/wk) or placebos were administered to the groups by an independent co-worker. After 8 wk, the athletes participated in a simulated soccer match, and perceived exertion and heart rates were measured during the trial. Blood samples were obtained presupplementation, postsupplementation, immediately after, and 2- and 24-h postexercise for measurement of lactate dehydrogenase, creatine phosphokinase, C-reactive protein (CRP), and interleukin (IL)-6.
Results
The intervention group demonstrated a significant increase in serum 25-hydroxyvitamin D levels (53.93, 10.68 ng/mL, P < 0.0001), which is the best indicator of vitamin D levels in the body, with no change in the circulating markers of muscle damage and CRP (P ˃ 0.05) but showed increased IL-6 (P = 0.034). In addition, the ratings of perceived exertion and heart rates were not altered by vitamin D compared with placebo ingestion (P = 0.155 versus P = 0.261; P = 0.600 versus P = 0.983).
Conclusion
The study showed that 50 000 IU/wk of cholecalciferol supplementation for 8 wk increased the 25-hydroxyvitamin D levels, with no effect on muscle damage indices or CRP. However, The IL-6 concentration was generally higher in the intervention group.
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