Photobiomodulation improves the frontal cognitive function of older adults
Chan AS, Lee TL, Yeung MK, Hamblin MR
International journal of geriatric psychiatry · 78 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute of Allergy and Infectious Diseases
- Gobierno
- NIAID NIH HHS
- Subvenciones
- National Institute of Allergy and Infectious Diseases (R01 AI050875); National Institute of Allergy and Infectious Diseases (R21 AI121700); National Institutes of Health (R01AI050875); National Institutes of Health (R21AI121700)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2018-11-26 · Int J Geriatr Psychiatry · vol. 34 · número 2 · págs. 369–377
- Editorial
- Wiley
- Citado
- 109 citas · más que el 96% de estudios similares · 4.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 81 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Photoreceptor and optogenetics research · Dental Health and Care Utilization
- Palabras clave
- Cognition, Gerontology, Psychology, Medicine, Physical medicine and rehabilitation, Neuroscience
- MeSH
- frontal lobe, humans, cognition, attention, aged, female, male, executive function, low-level light therapy
4 autores
- Agnes Sui-Yin Chan🇭🇰 · autor de correspondenciaChinese University of Hong Kong
- Tsz‐lok Lee🇭🇰Chinese University of Hong Kong
- Michael K. Yeung🇭🇰Chinese University of Hong Kong
- Michael R. Hamblin🇺🇸Harvard University; Massachusetts General Hospital; Harvard–MIT Division of Health Sciences and Technology
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
The frontal lobe hypothesis of age-related cognitive decline suggests that the deterioration of the prefrontal cortical regions that occurs with aging leads to executive function deficits. Photobiomodulation (PBM) is a newly developed, noninvasive technique for enhancing brain function, which has shown promising effects on cognitive function in both animals and humans. This randomized, sham-controlled study sought to examine the effects of PBM on the frontal brain function of older adults.
Methods/designs
Thirty older adults without a neuropsychiatric history performed cognitive tests of frontal function (ie, the Eriksen flanker and category fluency tests) before and after a single 7.5-minute session of real or sham PBM. The PBM device consisted of three separate light-emitting diode cluster heads (633 and 870 nm), which were applied to both sides of the forehead and posterior midline, and delivered a total energy of 1349 J.
Results
Significant group (experimental, control) × time (pre-PBM, post-PBM) interactions were found for the flanker and category fluency test scores. Specifically, only the older adults who received real PBM exhibited significant improvements in their action selection, inhibition ability, and mental flexibility after vs before PBM.
Conclusions
Our findings support that PBM may enhance the frontal brain functions of older adults in a safe and cost-effective manner.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.