Does Low-Level Laser Therapy Affect Recovery of Lingual and Inferior Alveolar Nerve Injuries?
Miloro M, Criddle TR
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 20 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of Nebraska Medical Center
- Universidad u hospital
- Aarhus Universitet
Según 2 financiadores declarados.
Publicación
- Publicado
- 2018-06-11 · J Oral Maxillofac Surg · vol. 76 · número 12 · págs. 2669–2675
- Editorial
- Elsevier BV
- Citado
- 42 citas · más que el 90% de estudios similares · 2.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 15 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Dental Radiography and Imaging · Dental Anxiety and Anesthesia Techniques
- Palabras clave
- low-level laser therapy, lingual nerve injury, inferior alveolar nerve injury, iatrogenic nerve injury, dental implant surgery, local anesthetic injection complications
- MeSH
- humans, postoperative complications, treatment outcome, follow-up studies, prospective studies, double-blind method, adult, female, male, trigeminal nerve injuries, low-level light therapy
2 autores
- Michael Miloro🇺🇸 · autor de correspondenciaUniversity of Illinois Chicago
- Thalia-Rae Criddle🇺🇸University of Illinois Chicago
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Iatrogenic damage to the inferior alveolar nerve (IAN) and lingual nerve (LN) may occur during routine oral and maxillofacial surgery procedures. The primary aim of this study was to determine, using a prospective, double-blind, randomized controlled clinical trial, whether the proportion of nerve-injured patients with postoperative neurosensory improvement over a 3-month period differed significantly between a control group and a low-level laser therapy (LLLT) group.
Patients and methods
The study sample consisted of 35 patients with iatrogenic nerve injury due to third molar odontectomy, dental implant placement, or local anesthetic injection. The investigators used a randomized, double-blind laser delivery system to administer either placebo or LLLT to patients who met the inclusion criteria. The outcome variable of neurosensory improvement was defined as a minimum 1-unit increase from baseline in visual analog scale rating and was based on standard objective clinical neurosensory testing. Study variables included the affected nerve (IAN or LN) and time from injury to treatment (3 to 12 months or >12 months). Univariate statistical analysis (χ2 test) was performed to determine significance between the groups.
Results
Neurosensory improvement was observed in 46.7% of the LLLT patients, who showed at least a 1-unit improvement at 3 months, compared with 38.5% improvement for controls (P = .66), regardless of the specific nerve involved (IAN or LN). In addition, no observed difference was noted between the study groups based on time from injury to treatment.
Conclusions
This study failed to provide sufficient evidence to conclude that a difference in neurosensory improvement exists between the LLLT and placebo groups with IAN or LN injuries. However, this study is unique in the prospective double-blind study design and comprehensive neurosensory testing protocols. There is a continued need for further clinical studies on LLLT in oral and maxillofacial surgery nerve injuries.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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