Financiado en parte por Cotton Incorporated
A 5-day high-fat diet rich in cottonseed oil improves cholesterol profiles and triglycerides compared to olive oil in healthy men
Polley KR, Oswell NJ, Pegg RB, Paton CM, Cooper JA
Nutrition research (New York, N.Y.) · 16 citas
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Alimentación controladaFinanciado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Cotton Incorporated
- Universidad u hospital
- AU/UGA Medical Partnership and UGA Clinical and Translational Research Unit
- Subvenciones
- Cotton Incorporated (AWD00003748)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2018-09-09 · Nutr Res · vol. 60 · págs. 43–53
- Editorial
- Elsevier BV
- Citado
- 24 citas · más que el 76% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 57 trabajos
- Acceso
- De pago
- Áreas de investigación
- Fatty Acid Research and Health · Nuts composition and effects · Edible Oils Quality and Analysis
- Palabras clave
- cottonseed oil, olive oil, dietary fat composition, high-fat diet, lipid profile, cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, postprandial lipemia, cardiovascular risk, short-term dietary intervention
- MeSH
- humans, cholesterol, cottonseed oil, triglycerides, fasting, area under curve, postprandial period, reference values, adolescent, adult, cholesterol, ldl, cholesterol, hdl, young adult, diet, high-fat, olive oil
5 autores
- Kristine R. Polley🇺🇸University of Georgia
- Natalie J. Oswell🇺🇸University of Georgia
- Ronald Bruce Pegg🇺🇸University of Georgia
- Chad Michael Paton🇺🇸University of Georgia
- Jamie A. Cooper🇺🇸 · autor de correspondenciaUniversity of Georgia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Modifying dietary fat composition is important for minimizing cardiovascular disease risk. The purpose of this study was to determine the effects of a 5-day, high-fat diet rich in cottonseed oil (CSO) or olive oil (OO) on lipid profiles. Based on previous human and animal models, we hypothesized that the CSO-rich diet would lead to lower fasting and postprandial lipid levels, whereas the OO-rich diet would not significantly change lipid levels in 5 days. Fifteen normal-weight men completed a randomized crossover design with 2 controlled feeding trials (3-day lead-in diet, prediet visit, 5-day CSO- or OO-rich diet, postdiet visit). The 5-day diets (50% fat) were rich in either CSO or OO. At pre- and postdiet visits, subjects consumed test meals rich in the oil that coincided with their 5-day diet, and blood draws were performed. Fasting total cholesterol, low-density lipoprotein cholesterol, and triglycerides (TG) were lower following CSO diet intervention (total cholesterol: 148.40 ± 6.39 to 135.93 ± 6.31 mg/dL; low-density lipoprotein cholesterol: 92.20 ± 5.57 to 78.13 ± 5.60 mg/dL; TG: 80.11 ± 4.91 to 56.37 ± 5.46 mg/dL for pre- to postdiet, respectively; P < .05). High-density lipoprotein cholesterol increased following CSO diet intervention (46.67 ± 2.41 to 50.24 ± 2.20 mg/dL for pre- to postdiet, respectively; P < .05). Postprandial TGs were lower following CSO diet (area under the curve of 954.28 ± 56.90 vs 722.16 ± 56.15 mg/dL/8 h for pre- vs postdiet, respectively; P < .01). No changes in blood lipids were found following OO diet. A 5-day CSO-rich diet led to improvements in cholesterol and TGs, whereas no changes were observed with an OO-rich diet.
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