Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists
McIlvenna LC, Muggeridge DJ, Forrest Nee Whyte LJ, Monaghan C, Liddle L, Burleigh MC, Sculthorpe N, Fernandez BO, Feelisch M, Easton C
Journal of science and medicine in sport · 4 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2019-01-27 · J Sci Med Sport · vol. 22 · número 7 · págs. 852–857
- Editorial
- Elsevier BV
- Citado
- 5 citas · más que el 73% de estudios similares · 0.8× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Cardiovascular and exercise physiology · Sports Performance and Training · Exercise and Physiological Responses
- Palabras clave
- ischemic preconditioning, nitrate supplementation, nitrite, time trial performance, cyclists, oxygen uptake kinetics, exercise performance, synergistic effect
- MeSH
- humans, nitrates, nitrites, ischemic preconditioning, cross-over studies, double-blind method, oxygen consumption, bicycling, adult, male, athletic performance, performance-enhancing substances, biomarkers
10 autores
- Luke C. McIlvenna🇦🇺🇬🇧Victoria University; University of the West of Scotland
- David J. Muggeridge🇬🇧University of the Highlands and Islands
- Laura J. Forrest🇬🇧University of the West of Scotland
- Chris Monaghan🇬🇧University of the West of Scotland
- Luke Liddle🇬🇧University of the West of Scotland
- Mia C. Burleigh🇬🇧University of the West of Scotland
- Nicholas F. Sculthorpe🇬🇧University of the West of Scotland
- Bernadette O. Fernandez🇬🇧University Hospital Southampton NHS Foundation Trust; National Institute for Health and Care Research; NIHR Southampton Biomedical Research Centre; University of Southampton
- Martin Feelisch🇬🇧University Hospital Southampton NHS Foundation Trust; National Institute for Health and Care Research; NIHR Southampton Biomedical Research Centre; University of Southampton
- Chris Easton🇬🇧 · autor de correspondenciaUniversity of the West of Scotland
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
Dietary nitrate (NO3-) supplementation and ischaemic preconditioning (IPC) can independently improve exercise performance. The purpose of this study was to explore whether NO3- supplementation, ingested prior to an IPC protocol, could synergistically enhance parameters of exercise.
Design
Double-blind randomized crossover trial.
Methods
Ten competitive male cyclists (age 34±6years, body mass 78.9±4.9kg, V⋅O2peak 55±4 mLkgmin-1) completed an incremental exercise test followed by three cycling trials comprising a square-wave submaximal component and a 16.1km time-trial. Oxygen uptake (V⋅O2) and muscle oxygenation kinetics were measured throughout. The baseline (BASE) trial was conducted without any dietary intervention or IPC. In the remaining two trials, participants received 3×5min bouts of lower limb bilateral IPC prior to exercise. Participants ingested NO3--rich gel (NIT+IPC) 90min prior to testing in one trial and a low NO3- placebo in the other (PLA+IPC). Plasma NO3- and nitrite (NO2-) were measured immediately before and after application of IPC.
Results
Plasma [NO3-] and [NO2-] were higher before and after IPC in NIT+IPC compared to BASE (P2 kinetics or muscle oxygenation parameters between trials (all P>0.4). Performance in the time-trial was similar between trials (BASE 1343±72s, PLA+IPC 1350±75s, NIT+IPC 1346±83s, P=0.98).
Conclusions
Pre-exercise IPC did not improve sub-maximal exercise or performance measures, either alone or in combination with dietary NO3- supplementation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.