The Additive Effects of Creatine Supplementation and Exercise Training in an Aging Population: A Systematic Review of Randomized Controlled Trials
Stares A, Bains M
Journal of geriatric physical therapy (2001) · 21 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2019-02-15 · J Geriatr Phys Ther · vol. 43 · número 2 · págs. 99–112
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 54 citas · más que el 68% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 50 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Cardiovascular and exercise physiology · Exercise and Physiological Responses
- Palabras clave
- Medicine, Creatine, Physical therapy, Randomized controlled trial, Physical medicine and rehabilitation, Training (meteorology), Population, Gerontology, Internal medicine, Environmental health
- MeSH
- muscle, skeletal, humans, creatine, cognition, sex factors, body composition, aging, bone density, dietary supplements, aged, muscle strength, randomized controlled trials as topic, resistance training, physical functional performance
2 autores
- Aaron Stares🇺🇸University of the Incarnate Word
- Mona Bains🇺🇸 · autor de correspondenciaUniversity of the Incarnate Word
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and purpose
The role of creatine supplementation in young athletes and bodybuilders is well established including ergogenic properties of muscular hypertrophy, strength, power, and endurance. Whether the benefits of creatine supplementation translate to an aging population with moderate training stimulus remains unclear especially in regard to gender, creatine dose, and duration. This systematic review assessed whether creatine supplementation combined with exercise results in additive improvements in indices of skeletal muscle, bone, and mental health over exercise alone in healthy older adults.
Methods
PubMed, CINAHL, and Web of Science databases were utilized to identify randomized controlled trials of creatine supplementation combined with exercise in an aging population with additional predetermined inclusion and exclusion criteria. Two reviewers independently screened the titles and abstracts, reviewed full-text articles, and performed quality assessments using the Physiotherapy Evidence Database scale.
Results and discussion
Seventeen studies were comprehensively reviewed according to categories of strength, endurance, functional capacity, body composition, cognition, and safety. These studies suggest that any additive ergogenic creatine effects on upper and/or lower body strength, functional capacity, and lean mass in an older population would require a continuous and daily low-dose creatine supplementation combined with at least 12 weeks of resistance training. Potential creatine specific increases in regional bone mineral density of the femur are possible but may require at least 1 year of creatine supplementation combined with moderate resistance training, and additional long-term clinical trials are warranted. The limited data suggested no additive effects of creatine over exercise alone on indices of mental health. The beneficial effects of creatine supplementation are more consistent in older women than in men.
Conclusions
Creatine monohydrate is safe to use in older adults. While creatine in conjunction with moderate- to high-intensity exercise in an aging population may improve skeletal muscle health, additional studies are needed to determine the effective dosing and duration paradigm for potential combined creatine and exercise effects on bone and cognition in older adults.
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