The effects of three regimens of cholecalciferol (vitamin D3) supplementation on vitamin D deficiency in non-obese and obese females
Imga NN, Berker D, Can B, Guler S
Archives of medical sciences. Atherosclerotic diseases · 7 citas
Cómo se estudió
- Diseño
- Ensayo clínico controlado (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2018-03-27 · Arch Med Sci Atheroscler Dis · vol. 3 · número 1 · págs. 60–67
- Editorial
- Termedia Publishing House
- Citado
- 8 citas · más que el 72% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 34 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY-NC-SA
- Áreas de investigación
- Vitamin D Research Studies · HIV-related health complications and treatments · Nutrition and Health Studies
- Palabras clave
- Medicine, Regimen, Vitamin D and neurology, Internal medicine, Cholecalciferol, vitamin D deficiency, Vitamin, Endocrinology, Gastroenterology, Intramuscular injection
4 autores
- Narin Nasıroğlu İmga🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Dilek Sensoz Berker🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Bülent Canbaz🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Serdar Güler🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Vitamin D deficiency is a common health problem worldwide and tends to be a risk factor for all-cause mortality. We evaluated the effect of continuous low-dose oral daily and loading dose of oral weekly and loading monthly intramuscular (IM) vitamin D3 regimens on circulating levels of total 25(OH)D and in vitamin D deficient females, and between non-obese and obese subgroups.
Material and methods
A total of 231 vitamin D deficient females were included to the study. According to treatment regimen, patients were divided into three groups: daily continuous oral, loading dose of weekly oral and monthly intramuscular. All patients in treatment groups were divided into non-obese (105) and obese (126) groups. Serum 25(OH)D and parathormone (PTH) levels were evaluated at baseline and at the third and sixth month.
Results
In obese patients oral weekly loading regimen and in non-obese patients oral daily continuous regimens were found to be more potent. Baseline PTH levels decreased when compared with the third and sixth months (p p = 0.783).
Conclusions
Oral daily regimen in non-obese patients and loading weekly oral regimen in obese patients were more effective in achieving the target levels of 25(OH)D concentration above 30 ng/ml and provided a stable plasma vitamin D concentration over a long period of time.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-SA).
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