Impact of red meat, processed meat and fibre intake on risk of late-onset chronic inflammatory diseases: prospective cohort study on lifestyle factors using the Danish 'Diet, Cancer and Health' cohort (PROCID-DCH): protocol
Rasmussen NF, Rubin KH, Stougaard M, Tjønneland A, Stenager E, Lund Hetland M, Glintborg B, Bygum A, Andersen V
BMJ open · 7 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoFinanciación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2019-03-01 · BMJ Open · vol. 9 · número 3 · pág. e024555
- Editorial
- BMJ
- Citado
- 8 citas · más que el 78% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 114 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC
- Áreas de investigación
- Nutritional Studies and Diet · Inflammatory Bowel Disease · Gut microbiota and health
- Palabras clave
- Medicine, Danish, Red meat, Prospective cohort study, Cohort study, Cohort, Environmental health, Epidemiology, Processed meat, Cancer, Internal medicine, Food science, Pathology
- MeSH
- humans, inflammatory bowel diseases, autoimmune diseases, chronic disease, health surveys, registries, risk factors, prospective studies, dietary fiber, middle aged, denmark, female, male, red meat, diet, healthy
9 autores
- Nathalie Fogh Rasmussen🇩🇰Aarhus University; Sygehus Sønderjylland
- Katrine Hass Rubin🇩🇰University of Southern Denmark; Odense University Hospital
- Maria Stougaard🇩🇰University of Southern Denmark; Odense University Hospital
- Anne Marie Tjønneland🇩🇰University of Copenhagen; Danish Cancer Society
- Egon Stenager🇩🇰University of Southern Denmark; Sygehus Sønderjylland
- Merete Lund Hetland🇩🇰Glostrup Hospital; Rigshospitalet
- Bente Glintborg🇩🇰Glostrup Hospital; Gentofte Hospital; Rigshospitalet
- Anette Bygum🇩🇰Odense University Hospital
- Vibeke Charlotte Andersen🇩🇰 · autor de correspondenciaUniversity of Southern Denmark; Sygehus Sønderjylland
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Chronic inflammatory diseases (CIDs) (Crohn's disease, ulcerative colitis, psoriasis, psoriatic arthritis, rheumatoid arthritis and multiple sclerosis) are diseases of the immune system that have some shared genetic and environmental predisposing factors, but still few studies have investigated the effects of lifestyle on disease risk of several CIDs. The primary aim of this prospective cohort study is to investigate the impact of fibre, red meat and processed meat on risk of late-onset CID, with the perspective that results of this study can contribute in supporting future diet recommendations for effective personalised prevention.
Methods and analysis
The study will use data from 57 053 persons from the prospective Danish cohort study 'Diet, Cancer and Health' together with National Health Registry data. The follow-up period is from December 1993 to December 2018. Questionnaire data on diet and lifestyle were collected at entry to the Diet, Cancer and Health study. The outcome CID is defined as having a diagnosis of one of the CIDs registered in the National Patient Registry or, for multiple sclerosis, in the Danish Multiple Sclerosis Registry during follow-up and being treated with a drug used for the specific disease. The major outcome of the analyses will be to detect variability in risk of late onset of any CID and, if power allows, disease risk of late onset of each CID diagnosis between persons with different fibre and red meat, and processed meat intake. The outcome will be adjusted for age, sex, body mass index, physical activity, energy, alcohol, fermented dairy products, education, smoking status, hormone replacement therapy and comorbidity.
Ethics and dissemination
The study is approved by the Danish Data Protection Agency (2012-58-0018). The core study is an open register-based cohort study. The study does not need approval from the Ethics committee or Institutional Review Board by Danish law. Study findings will be disseminated through peer-reviewed journals, patient associations and presentations at international conferences.
Trial registration number
NCT03456206; Post-results.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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