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Estudio de casos y controles2018Financiación no declaradaSin ajuste declarado por estilo de vida

Associations between higher egg consumption during pregnancy with lowered risks of high blood pressure and gestational diabetes mellitus

Milajerdi A, Tehrani H, Haghighatdoost F, Larijani B, Surkan PJ, Azadbakht L

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 14 citas

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Cómo se estudió

Diseño
Estudio de casos y controles (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2018-06-01 · Int J Vitam Nutr Res · vol. 88 · número 3-4 · págs. 166–175
Editorial
Hogrefe Verlag
Citado
16 citas · más que el 80% de estudios similares · 1.4× el promedio de su campo
Referencias
37 trabajos
Acceso
De pago
Áreas de investigación
Gestational Diabetes Research and Management · Birth, Development, and Health · Diet and metabolism studies
Palabras clave
Gestational diabetes, Medicine, Odds ratio, Confidence interval, Pregnancy, Cholesterol, Diabetes mellitus, Blood pressure, Logistic regression, Obstetrics, Odds, Internal medicine, Endocrinology, Gestation, Biology
MeSH
ovum, humans, diabetes, gestational, hypertension, risk factors, case-control studies, pregnancy, child, iran, female

6 autores

  • Alireza Milajerdi🇮🇷Tehran University of Medical Sciences
  • Hatav Ghasemi Tehrani🇮🇷Isfahan University of Medical Sciences
  • Fahimeh Haghighatdoost🇮🇷Isfahan University of Medical Sciences
  • Bagher A. Larijani🇮🇷Tehran University of Medical Sciences
  • Pamela Jean Surkan
  • Leila Azadbakht🇮🇷Isfahan University of Medical Sciences; Endocrinology and Metabolism Clinical Sciences Institute; Tehran University of Medical Sciences

Resumen

El texto original del estudio, en el idioma en que se publicó.

Introduction: The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide. High cholesterol intake may increase the risk of hyperglycemia, yet little research has evaluated the relation between cholesterol or egg as a main source of dietary cholesterol and GDM. We aimed to study this association among pregnant Iranian women. Methods and Participants: Four hundred sixty-two pregnant women participated in this case-control study. Participants' dietary intake, weight, height, and blood pressure were obtained and BMI was calculated. Fasting plasma glucose and liver enzymes were also measured. Logistic regression was used to obtain odds ratios and 95% confidence intervals for GDM across tertiles of cholesterol and egg consumption. Results: Among study participants, 115 consumed less than one, 194 consumed one and the remaining participants consumed more than one egg per week (mean cholesterol intake 121.31±61.69 mg/d). Participants within the highest tertile of egg consumption had 41% lower risk of GDM (OR: 0.59; 95% CI: 0.35-0.99) compared with those in the lowest tertile (P=0.01). Higher egg consumption was associated with lower risk of having high blood pressure (P=0.01). The difference in odds of GDM and high blood pressure between the highest and the lowest tertile of cholesterol consumption was not significant, even after controlling for age, energy intake, number of children and socio-economic status. Conclusion: Higher dietary intake of egg during pregnancy was associated with lower odds of GDM. We found no significant association between cholesterol intake and odds of GDM. Further research are needed to confirm these results and determine causality.

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