Tumor safety and side effects of photobiomodulation therapy used for prevention and management of cancer treatment toxicities. A systematic review
de Pauli Paglioni M, Araújo ALD, Arboleda LPA, Palmier NR, Fonsêca JM, Gomes-Silva W, Madrid-Troconis CC, Silveira FM, Martins MD, Faria KM, Ribeiro ACP, Brandão TB, Lopes MA, Leme AFP, Migliorati CA, Santos-Silva AR
Oral oncology · 68 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- São Paulo Research Foundation (FAPESP), Brazil
Según 1 financiador declarado.
Publicación
- Publicado
- 2019-04-10 · Oral Oncol · vol. 93 · págs. 21–28
- Editorial
- Elsevier BV
- Citado
- 109 citas · más que el 89% de estudios similares · 2.2× el promedio de su campo
- Referencias
- 59 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Oral health in cancer treatment · Photodynamic Therapy Research Studies
- Palabras clave
- low-level laser therapy, cancer treatment toxicity, second primary tumors, breast cancer-related lymphedema, oral mucositis, radiation dermatitis, peripheral neuropathy, treatment side effects
- MeSH
- humans, neoplasms, stomatitis, lymphedema, treatment outcome, randomized controlled trials as topic, low-level light therapy
16 autores
- Mariana de Pauli Paglioni🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Anna Luíza Damaceno Araújo🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Lady Paola Aristizábal Arboleda🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Natália Rangel Palmier🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Jéssica Montenegro Fonsêca🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Wagner Gomes da Silva🇧🇷Universidade Nove de Julho; Instituto do Câncer do Estado de São Paulo
- Cristhian Camilo Madrid Troconis🇧🇷🇨🇴Universidade Estadual de Campinas (UNICAMP); Corporación Universitaria Rafael Nuñez
- Felipe Martins Silveira🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Manoela Domingues Martins🇧🇷Universidade Federal do Rio Grande do Sul; Universidade Estadual de Campinas (UNICAMP)
- Karina Morais Faria🇧🇷Instituto do Câncer do Estado de São Paulo
- Ana Carolina Prado Ribeiro🇧🇷Instituto do Câncer do Estado de São Paulo
- Thaís Bianca Brandão🇧🇷Instituto do Câncer do Estado de São Paulo
- Márcio Ajudarte Lopes🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Adriana Franco Paes Leme🇧🇷Brazilian Center for Research in Energy and Materials; Brazilian Biosciences National Laboratory
- Cesar Augusto Migliorati🇺🇸University of Florida
- Alan Roger Santos‐Silva🇧🇷 · autor de correspondenciaUniversidade Estadual de Campinas (UNICAMP)
Resumen
El texto original del estudio, en el idioma en que se publicó.
Photobiomodulation therapy (PBMT), also known as low-level laser therapy (LLLT), has been increasingly used for the treatment of toxicities related to cancer treatment. One of the challenges for the universal acceptance of PBMT use in cancer patients is whether or not there is a potential for the light to stimulate the growth of residual malignant cells that evaded oncologic treatment, increasing the risk for tumor recurrences and development of a second primary tumor. Current science suggests promising effects of PBMT in the prevention and treatment of breast cancer-related lymphedema and oral mucositis, among other cancer treatment toxicities. Nevertheless, this seems to be the first systematic review to analyze the safety of the use of PBMT for the management of cancer-related toxicities. Scopus, MEDLINE/PubMed, and Embase were searched electronically. A total of 27 articles met the search criteria. Selected studies included the use of PBMT for prevention and treatment of oral mucositis, lymphedema, radiodermatitis, and peripheral neuropathy. Most studies showed that no side effects were observed with the use of PBMT. The results of this systematic review, based on current literature, suggest that the use of PBMT in the prevention and management of cancer treatment toxicities does not lead to the development of tumor safety issues.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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