Association between nut consumption and non-alcoholic fatty liver disease in adults
Zhang S, Fu J, Zhang Q, Liu L, Meng G, Yao Z, Wu H, Bao X, Gu Y, Lu M, Sun S, Wang X, Zhou M, Jia Q, Song K, Xiang H, Wu Y, Niu K
Liver international : official journal of the International Association for the Study of the Liver · 44 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Subvenciones
- National Natural Science Foundation of China (81,673,166); National Natural Science Foundation of China (81872611); National Natural Science Foundation of China (91,746,205)
Según 1 financiador declarado.
Publicación
- Publicado
- 2019-06-04 · Liver Int · vol. 39 · número 9 · págs. 1732–1741
- Editorial
- Wiley
- Citado
- 53 citas · más que el 95% de estudios similares · 4.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 46 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Oral Health Pathology and Treatment · Peanut Plant Research Studies
- Palabras clave
- Medicine, Fatty liver, Odds ratio, Internal medicine, Metabolic syndrome, Confidence interval, Population, Nut, Refined grains, Insulin resistance, Prospective cohort study, Confounding, Disease, Gastroenterology, Obesity, Environmental health, Food science, Biology
- MeSH
- humans, nuts, diet, logistic models, odds ratio, prospective studies, cross-sectional studies, life style, energy intake, adult, china, female, male, non-alcoholic fatty liver disease
18 autores
- Shunming Zhang🇨🇳Tianjin Medical University
- Jingzhu Fu🇨🇳Tianjin Medical University
- Qing Zhang🇨🇳Tianjin Medical University General Hospital
- Li Liu🇨🇳Tianjin Medical University General Hospital
- Ge Meng🇨🇳Tianjin Medical University
- Zhanxin Yao🇨🇳Tianjin Medical University
- Hongmei Wu🇨🇳Tianjin Medical University
- Xue Bao🇨🇳Tianjin Medical University
- Yeqing Gu🇨🇳Tianjin Medical University
- Min M. Lu🇨🇳Tianjin Medical University
- Shaomei Sun🇨🇳Tianjin Medical University General Hospital
- Xing Wang🇨🇳Tianjin Medical University General Hospital
- Ming Yue Zhou🇨🇳Tianjin Medical University General Hospital
- Qiyu Jia🇨🇳Tianjin Medical University General Hospital
- Kun Song🇨🇳Tianjin Medical University General Hospital
- Huiling Xiang🇨🇳Tianjin Third Central Hospital; Tianjin Medical University
- Yuntang Wu🇨🇳 · autor de correspondenciaTianjin Medical University
- Kaijun Niu🇨🇳 · autor de correspondenciaTianjin Medical University General Hospital; Tianjin Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background & aims
Increased nut consumption has been associated with reduced inflammation, insulin resistance, and oxidative stress. Although these factors are closely involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), few studies have focused on the association between nut consumption and NAFLD in the general population. We aimed to investigate the association of nut consumption and NAFLD in an adult population.
Methods
A total of 23 915 participants from Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) Cohort Study were included in this study. Information on dietary intake was collected using a validated food frequency questionnaire. Abdominal ultrasonography was done to diagnose NAFLD. Multivariable logistic regression was used to assess the association of nut consumption with NAFLD.
Results
After adjusting for sociodemographic, medical, dietary, and lifestyle variables, the odds ratios (95% confidence interval) for NAFLD across categories of nut consumption were 1.00 (reference) for <1 time/week, 0.91 (0.82, 1.02) for 1 time/week, 0.88 (0.76, 1.02) for 2-3 times/week, and 0.80 (0.69, 0.92) for ≥4 times/week (P for trend < 0.01). These associations were attenuated but remained significant after further adjustment for blood lipids, glucose, and inflammation markers.
Conclusions
Higher nut consumption was significantly associated with lower prevalence of NAFLD. Further prospective studies and randomized trials are required to ascertain the causal association between nut consumption and NAFLD.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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