The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study
Anton SD, Lee SA, Donahoo WT, McLaren C, Manini T, Leeuwenburgh C, Pahor M
Nutrients · 187 citas
Cómo se estudió
- Diseño
- Ensayo clínico controlado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute on Aging
- Universidad u hospital
- Duke Claude D. Pepper Older Americans Independence Center, Duke Aging Center, Duke University
- Universidad u hospital
- Claude D. Pepper Older Americans Independence Center
- Gobierno
- NIA NIH HHS
- Subvenciones
- Duke Claude D. Pepper Older Americans Independence Center, Duke Aging Center, Duke University (P30AG028740); National Institute on Aging (P30 AG028740); National Institutes of Health (P30AG028740)
Según 5 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2019-06-30 · Nutrients · vol. 11 · número 7 · pág. 1500
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 233 citas · más que el 99% de estudios similares · 13.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 29 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Genetics, Aging, and Longevity in Model Organisms
- Palabras clave
- Overweight, Weight loss, Medicine, Waist, Adverse effect, Obesity, Quality of life (healthcare), Calorie restriction, Intermittent fasting, Gerontology, Intervention (counseling), Physical therapy, Internal medicine
- MeSH
- humans, weight loss, gait, treatment outcome, fasting, feasibility studies, pilot projects, feeding behavior, age factors, health status, recovery of function, energy intake, time factors, quality of life, aged, female, male, overweight, mobility limitation, sedentary behavior
7 autores
- Stephen Douglas Anton🇺🇸 · autor de correspondenciaUniversity of Florida Health; University of Florida; Institute on Aging
- Stephanie A. Lee🇺🇸University of Florida; Institute on Aging
- William Troy Donahoo🇺🇸University of Florida; Florida College
- Christian McLaren🇺🇸University of Florida; Institute on Aging
- Todd Matthew Manini🇺🇸University of Florida; Institute on Aging
- Christiaan Leeuwenburgh🇺🇸University of Florida Health; University of Florida; Institute on Aging
- Marco Pahor🇺🇸University of Florida; Institute on Aging
Resumen
El texto original del estudio, en el idioma en que se publicó.
A growing body of evidence indicates that time restricted feeding (TRF), a popular form of intermittent fasting, can activate similar biological pathways as caloric restriction, the only intervention consistently found to extend healthy lifespan in a variety of species. Thus, TRF may have the potential to also improve function in older adults. Given the challenges many individuals have in following calorie restriction regimens over long-time periods, evaluation of alternative approaches that may produce weight loss and improve function in overweight, older adults is important. Ten overweight, sedentary older adults (≥65 years) at risk for, or with mobility impairments, defined by slow gait speed (p < 0.01). Since body composition was not measured in this study, it is unclear if the observed weight loss was due to loss of fat mass, muscle mass, or the combination of fat and muscle mass. There were no significant changes in other outcomes; however, there were clinically meaningful changes in walking speed and improvements in quality of life, with few reported adverse events. The findings of this pilot study suggest that time restricted feeding is an acceptable and feasible eating pattern for overweight, sedentary older adults to follow.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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