Is photobiomodulation therapy effective in reducing pain caused by toxicities related to head and neck cancer treatment? A systematic review
de Pauli Paglioni M, Alves CGB, Fontes EK, Lopes MA, Ribeiro ACP, Brandão TB, Migliorati CA, Santos-Silva AR
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 19 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Subvenciones
- Fundação de Amparo à Pesquisa do Estado de São Paulo (12/06138-1); Fundação de Amparo à Pesquisa do Estado de São Paulo (13/18402-8); Fundação de Amparo à Pesquisa do Estado de São Paulo (18/02233-6)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2019-07-01 · Support Care Cancer · vol. 27 · número 11 · págs. 4043–4054
- Editorial
- Springer Science+Business Media
- Citado
- 31 citas · más que el 70% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 51 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · OTHER-OA
- Áreas de investigación
- Oral health in cancer treatment · Laser Applications in Dentistry and Medicine · Head and Neck Cancer Studies
- Palabras clave
- low-level laser therapy, head and neck cancer, cancer pain, oral mucositis, radiation dermatitis, radiotherapy toxicity, chemotherapy toxicity, analgesic use, pain management
- MeSH
- humans, head and neck neoplasms, stomatitis, pain, female, male, low-level light therapy
8 autores
- Mariana de Pauli Paglioni🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Carolina Guimarães Bonfim Alves🇧🇷Universidade Estadual de Campinas (UNICAMP)
- ELISA KAUARK FONTES🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Márcio Ajudarte Lopes🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Ana Carolina Prado Ribeiro🇧🇷Universidade Estadual de Campinas (UNICAMP); Instituto do Câncer do Estado de São Paulo
- Thaís Bianca Brandão🇧🇷Instituto do Câncer do Estado de São Paulo
- Cesar Augusto Migliorati🇺🇸University of Florida
- Alan Roger Santos‐Silva🇧🇷 · autor de correspondenciaUniversidade Estadual de Campinas (UNICAMP)
Resumen
El texto original del estudio, en el idioma en que se publicó.
Photobiomodulation therapy (PBMT) has been considered an effective method for preventing and managing certain cancer-related toxicities in head and neck cancer (HNC) patients treated with radiotherapy and chemotherapy. However, the potential effects of PBMT on pain control and analgesia resulting from these toxicities is still controversial. The aim of this systematic review was to compile available evidence of the effects of PMBT on pain control and reduced use of analgesics in HNC patients. We searched three indexed databases: MEDLINE/PubMed, Embase, and Scopus. The databases were reviewed up to and including December 2018. Only human clinical studies in English language were selected. Information was only available for mucositis and radiodermatitis. Fifteen out of 1112 studies met the inclusion criteria (14 for oral mucositis (OM) and 1 for radiodermatitis). From the 14 studies involving the prevention and treatment of OM, 10 had the study subjects compared to a placebo group. Of these 10 studies, all but 1 showed statistically significant difference related to pain control favoring the PBMT group. The study that compared PBMT with other treatment modality showed better results in pain control with PBMT. It appears that PBMT application frequency and potency impact on pain control. The only study involving the prevention and treatment of radiodermatitis was compared to placebo arm and showed statistically significant difference related to pain control favoring the PBMT group. Seven studies compared the need of analgesic medication between PBMT and placebo groups. Of these, five studies showed that the use of analgesic medication was significantly higher in the placebo group. The current evidence supports that PBMT is effective in pain control resulting from OM and radiodermatitis and may also reduce the need for analgesics. The evidence is not yet available of the effects of PBMT in other HNC treatment-related toxicities.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.