Financiado en parte por MTI Biotech, MTI Biotech Inc.
Time-restricted feeding plus resistance training in active females: a randomized trial
Tinsley GM, Moore ML, Graybeal AJ, Paoli A, Kim Y, Gonzales JU, Harry JR, VanDusseldorp TA, Kennedy DN, Cruz MR
The American journal of clinical nutrition · 176 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Universidad u hospital
- Texas Tech University
- Empresa
- MTI Biotech
- Empresa
- MTI Biotech Inc.
Según 3 financiadores declarados.
Publicación
- Publicado
- 2019-05-31 · Am J Clin Nutr · vol. 110 · número 3 · págs. 628–640
- Editorial
- Elsevier BV
- Citado
- 224 citas · más que el 99% de estudios similares · 12.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 58 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Muscle metabolism and nutrition
- Palabras clave
- Calorie, Randomized controlled trial, Medicine, Placebo, Internal medicine, Animal science, Endocrinology, Resistance training, Muscle hypertrophy, Biology
- MeSH
- humans, body composition, time factors, adult, female, resistance training, young adult, meals
10 autores
- Grant M. Tinsley🇺🇸 · autor de correspondenciaTexas Tech University
- Michael Lane Moore🇺🇸Texas Tech University
- Austin J. Graybeal🇺🇸Texas Tech University
- Antonio Paoli🇮🇹University of Padua
- Youngdeok Kim🇺🇸Texas Tech University
- Joaquin U. Gonzales🇺🇸Texas Tech University
- John R. Harry🇺🇸Texas Tech University
- Trisha A. VanDusseldorp🇺🇸Kennesaw State University
- Devin N Kennedy🇺🇸Texas Tech University
- Megan R. Cruz🇺🇸Texas Tech University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
A very limited amount of research has examined intermittent fasting (IF) programs, such as time-restricted feeding (TRF), in active populations.
Objective
Our objective was to examine the effects of TRF, with or without β-hydroxy β-methylbutyrate (HMB) supplementation, during resistance training (RT).
Methods
This study employed a randomized, placebo-controlled, reduced factorial design and was double-blind with respect to supplementation in TRF groups. Resistance-trained females were randomly assigned to a control diet (CD), TRF, or TRF plus 3 g/d HMB (TRFHMB). TRF groups consumed all calories between 1200 h and 2000 h, whereas the CD group ate regularly from breakfast until the end of the day. All groups completed 8 wk of supervised RT and consumed supplemental whey protein. Body composition, muscular performance, dietary intake, physical activity, and physiological variables were assessed. Data were analyzed prior to unblinding using mixed models and both intention-to-treat (ITT) and per protocol (PP) frameworks.
Results
Forty participants were included in ITT, and 24 were included in PP. Energy and protein intake (1.6 g/kg/d) did not differ between groups despite different feeding durations (TRF and TRFHMB: ∼7.5 h/d; CD: ∼13 h/d). Comparable fat-free mass (FFM) accretion (+2% to 3% relative to baseline) and skeletal muscle hypertrophy occurred in all groups. Differential effects on fat mass (CD: +2%; TRF: -2% to -4%; TRFHMB: -4% to -7%) were statistically significant in the PP analysis, but not ITT. Muscular performance improved without differences between groups. No changes in physiological variables occurred in any group, and minimal side effects were reported.
Conclusions
IF, in the form of TRF, did not attenuate RT adaptations in resistance-trained females. Similar FFM accretion, skeletal muscle hypertrophy, and muscular performance improvements can be achieved with dramatically different feeding programs that contain similar energy and protein content during RT. Supplemental HMB during fasting periods of TRF did not definitively improve outcomes. This study was prospectively registered at clinicaltrials.gov as NCT03404271.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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