Effectiveness of Low-Level Laser Therapy with a 915 Nm Wavelength Diode Laser on the Healing of Intraoral Mucosal Wound: An Animal Study and a Double-Blind Randomized Clinical Trial
Choung HW, Lee SH, Ham AR, Lee NR, Kim B, Pang KM, Jahng JW, Lee JH
Medicina (Kaunas, Lithuania) · 17 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas, más trabajo en animales o laboratorio
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Korea Health Industry Development Institute
- Subvenciones
- Korea Health Industry Development Institute (HI15C1535)
Según 1 financiador declarado.
Publicación
- Publicado
- 2019-07-24 · Medicina (Kaunas) · vol. 55 · número 8 · pág. 405
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 29 citas · más que el 85% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Wound Healing and Treatments · Biofield Effects and Biophysics
- Palabras clave
- low-level laser therapy, third molar extraction, postoperative wound dehiscence, wound healing, inflammatory parameters, adjunctive therapy
- MeSH
- mucous membrane, molar, third, animals, humans, rats, rats, sprague-dawley, disease models, animal, treatment outcome, analysis of variance, double-blind method, wound healing, adolescent, adult, female, male, young adult, republic of korea, low-level light therapy
8 autores
- Han‐Wool Choung🇰🇷Seoul National University; Seoul National University Dental Hospital
- Sung-Ho Lee🇰🇷Seoul National University; Seoul National University Dental Hospital
- Ahe Reum Ham🇰🇷Seoul National University; Seoul National University Dental Hospital
- Na Ra Lee🇰🇷Dentium (South Korea)
- Bongju Kim🇰🇷Seoul National University Dental Hospital
- Kang‐Mi Pang🇰🇷Seoul National University; Seoul National University Gwanak Dental Hospital
- Jeong Won Jahng🇰🇷Seoul National University; Seoul National University Dental Hospital
- Jong-Ho Lee🇰🇷 · autor de correspondenciaSeoul National University; Seoul National University Dental Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and objectives: Diode laser has been the most popular low-level laser therapy (LLLT) technique in dentistry due to its good tissue penetration, lower financial costs, small size for portable application, and convenience to use. A series of recent studies with 940 nm or 980 nm lasers demonstrated that LLLT showed positive effects after third molar extraction or periodontal flap surgery. However, the effects of LLLT on intraoral mucosal wound healing after surgical incision have not yet been determined in human clinical study. Materials and Methods: The present study was performed to determine the efficacy and safety of 915 nm wavelength low-level laser therapy (LLLT) in mucosal wound healing. A total of 108 Sprague-Dawley rats were used. They were divided into three groups: Abrasive wound group, immediate LLLT once group, and daily LLLT group. As a clinical study, a total of 16 patients with split-mouth design subjected to bilateral mandibular third molar extraction were allocated into the LLLT group and placebo group. The process of LLLT was performed on postoperative days 0, 1, and 7, and parameters related to wound healing were analyzed on days 1, 7, and 14. Results: Repeated laser irradiation promoted mucosal wound healing of the rats. In the clinical study, although there were no significant statistical differences between the LLLT and placebo groups in all inflammatory parameters, the early stage mucosal healing tendency of wound dehiscence was higher in the LLLT group than in the placebo group clinically on postoperative day 1. Conclusions: The present results showed that 915 nm LLLT could be applied safely as an auxiliary therapy for mucosal wound healing.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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