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Ensayo controlado aleatorizado2019

Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial

Motaharifard MS, Effatpanah M, Karimi M, Akhondzadeh S, Rahimi H, Yasrebi SA, Nejatbakhsh F

Complementary therapies in clinical practice · 14 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
Clinical Trial Center, China Medical University Hospital
Universidad u hospital
Tehran University of Medical Sciences and Health Services
Subvenciones
Tehran University of Medical Sciences and Health Services (95-01-86-31723)

Según 2 financiadores declarados.

Publicación

Publicado
2019-07-19 · Complement Ther Clin Pract · vol. 36 · págs. 170–175
Editorial
Elsevier BV
Citado
18 citas · más que el 76% de estudios similares · 1.1× el promedio de su campo
Referencias
48 trabajos
Acceso
De pago
Áreas de investigación
Attention Deficit Hyperactivity Disorder · Complementary and Alternative Medicine Studies · Medicinal Plant Extracts Effects
Palabras clave
attention deficit hyperactivity disorder, methylphenidate, Persian medicine, children, ADHD symptom reduction, treatment efficacy, drug safety
MeSH
humans, methylphenidate, central nervous system stimulants, plant extracts, antioxidants, double-blind method, attention deficit disorder with hyperactivity, adolescent, child, female, male, functional food, prunus dulcis

7 autores

  • Monireh Sadat Motaharifard🇮🇷Tehran University of Medical Sciences
  • Mohammad Effatpanah🇮🇷Ziaeian Hospital; Tehran University of Medical Sciences
  • Mehrdad Karimi🇮🇷Tehran University of Medical Sciences
  • Shahin Akhondzadeh🇮🇷Roozbeh Hospital; Tehran University of Medical Sciences
  • Habibollah Rahimi🇮🇷Kashan University of Medical Sciences
  • Seyed Ali Yasrebi🇮🇷Ferdowsi University of Mashhad
  • Fatemeh Nejatbakhsh🇮🇷 · autor de correspondenciaTehran University of Medical Sciences

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background and purpose

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common health disorders among children. Some patients do not respond to methylphenidate or cannot tolerate its side effects. Sweet almond syrup as a Persian Medicine preparation has been used for many years. This study aims to evaluate the efficacy and safety of sweet almond for ADHD children.

Materials and methods

Fifty children aged 6-14 years with ADHD were recruited to the study. The participants were randomly assigned to two groups to receive either methylphenidate or sweet almond syrup. The outcomes were assessed using the Parent and Teacher ADHD Rating Scale every two weeks for 8 weeks.

Results

Results showed that the two treatments had similar effects on symptom reduction in ADHD children. No significant differences were observed between the two groups (F=2.3, df=1, p=0.13, F=0.57, df=1, p=0.47).

Conclusion

Sweet almond may be an effective treatment for ADHD children.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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