Effects of dietary whole grain, fruit, and vegetables on weight and inflammatory biomarkers in overweight and obese women
Arabzadegan N, Daneshzad E, Fatahi S, Moosavian SP, Surkan PJ, Azadbakht L
Eating and weight disorders : EWD · 18 citas
Etiquetas de revisión
Alimentación controladaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Isfahan University of Medical Sciences
Según 1 financiador declarado.
Publicación
- Publicado
- 2019-08-09 · Eat Weight Disord · vol. 25 · número 5 · págs. 1243–1251
- Editorial
- Springer Science+Business Media
- Citado
- 26 citas · más que el 91% de estudios similares · 2.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 45 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Food composition and properties · Adipokines, Inflammation, and Metabolic Diseases
- Palabras clave
- whole grain diet, fruit and vegetable diet, high-fiber diet, obesity, overweight women, inflammation, inflammatory markers, C-reactive protein, TNF-α, interleukin-6, fibrinogen, D-dimer, malondialdehyde, weight loss
- MeSH
- humans, fruit, vegetables, obesity, diet, female, overweight, biomarkers, whole grains
6 autores
- Niloufar Arabzadegan🇮🇷Tehran University of Medical Sciences
- Elnaz Daneshzad🇮🇷Tehran University of Medical Sciences
- Somayeh Fatahi🇮🇷Tehran University of Medical Sciences
- Seyedeh Parisa Moosavian🇮🇷Isfahan University of Medical Sciences
- Pamela J. Surkan🇺🇸Johns Hopkins University
- Leila Azadbakht🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences; Endocrinology and Metabolism Clinical Sciences Institute; Diabetes Research Center; Tehran University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
The separate effects of whole grain (WG) and fruit and vegetable (F&V) diets on inflammatory biomarkers have not been assessed. Therefore, we evaluated these two high-fiber diets in relation to inflammation indices in obese and overweight women.
Study design
Parallel randomized clinical trial.
Methods
In the present study, 75 women were recruited and randomly assigned to three diet groups: a whole grain diet (WG-D) group, F&V group, and a combined whole grain and F&V diet group (WGFV-D) for 10 weeks. As a "feeding trial" all participants were asked to visit the clinic daily and eat prescribed foods in the presence of a nutritionist. Anthropometric indices and biochemical biomarkers were measured at baseline and after 10 weeks of the trial.
Results
Each of the three diet groups showed significant changes in serum biomarkers (CRP, TNF-α, IL-6, D-dimer, and serum fibrinogen) after following the diet for 10 weeks (P = 0.01). In adjusted models, significant changes were observed for CRP, TNF-α, IL-6, D-dimer, and serum fibrinogen (P = 0.01). In a model adjusted for malondialdehyde (MDA) level, a trend toward significance was observed (P = 0.05). Consumption of all three different diets for 10 weeks showed statistically significant change for all biomarkers (P < 0.05) the most notable changes in inflammatory indices were observed among participants following the WG diet.
Conclusions
Study results indicate that consumption of high-fiber diets, especially the WG diet, can help lower inflammatory levels and prevent subsequent adverse health consequences.
Level of evidence
Level I, randomized controlled trial.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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