Effect of omega-3 fatty acids and fish oil supplementation on multiple sclerosis: a systematic review
AlAmmar WA, Albeesh FH, Ibrahim LM, Algindan YY, Yamani LZ, Khattab RY
Nutritional neuroscience · 85 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2019-08-28 · Nutr Neurosci · vol. 24 · número 7 · págs. 569–579
- Editorial
- Taylor & Francis
- Citado
- 117 citas · más que el 87% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- Multiple Sclerosis Research Studies · Fatty Acid Research and Health · Pediatric health and respiratory diseases
- Palabras clave
- Fish oil, Multiple sclerosis, Medicine, Polyunsaturated fatty acid, Randomized controlled trial, Internal medicine, Physiology, Fish <Actinopterygii>, Gastroenterology, Bioinformatics, Biology, Fatty acid, Immunology, Biochemistry
- MeSH
- humans, multiple sclerosis, fatty acids, omega-3, fish oils, dietary supplements, female, male
6 autores
- Welayah Ali AlAmmar🇸🇦Imam Abdulrahman Bin Faisal University
- Fatima H. Albeesh🇸🇦Imam Abdulrahman Bin Faisal University
- Layla Makki Ibrahim🇸🇦Imam Abdulrahman Bin Faisal University
- Yasmin Algindan🇸🇦Imam Abdulrahman Bin Faisal University
- Lamya Zohair Yamani🇸🇦Imam Abdulrahman Bin Faisal University
- Rabie Yousif Khattab🇸🇦 · autor de correspondenciaImam Abdulrahman Bin Faisal University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background: Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system, resulting in the degradation of the myelin sheath. Diet especially fish oils and omega-3 has been found to play an important role in MS. This work aimed to review the literature systematically for evidence on the effect of omega-3 fatty acids (EPA, DPA and DHA) on MS progression in adults.Methods: The literature search was conducted in PubMed, Oxford, Cochrane, Embase, International pharmaceutical abstract, PsychINFO, and clinical trials government. The inclusions were studies performed on humans both male and female, aged 18 years at minimum, diagnosed with MS according to McDonald 2010 criteria. Otherwise, all studies were excluded.Results: A total of 5554 studies were screened and seven were thoroughly focused on as they typically met the inclusion criteria. These studies showed the beneficial roles of fish oil supplementation and omega-3 fatty acids in improving the quality of life of MS patients. These roles were attributed to their beneficial effects on inflammatory markers, glutathione reductase, reducing the relapsing rate, and achieving balanced omega-6 to omega-3 ratios.Conclusion: Omega-3 and fish oils supplementations have beneficial effects on reducing the relapsing rate, inflammatory markers, and improving the quality of life for MS patients.
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