Patterns of Red and Processed Meat Consumption and Risk for Cardiometabolic and Cancer Outcomes: A Systematic Review and Meta-analysis of Cohort Studies
Vernooij RWM, Zeraatkar D, Han MA, El Dib R, Zworth M, Milio K, Sit D, Lee Y, Gomaa H, Valli C, Swierz MJ, Chang Y, Hanna SE, Brauer PM, Sievenpiper J, de Souza R, Alonso-Coello P, Bala MM, Guyatt GH, Johnston BC
Annals of internal medicine · 92 citas
Etiquetas de revisión
Financiación no declaradaMezcla carne procesada con no procesadaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2019-10-01 · Ann Intern Med · vol. 171 · número 10 · págs. 732–741
- Editorial
- American College of Physicians
- Citado
- 153 citas · más que el 100% de estudios similares · 21.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY-NC-ND
- Áreas de investigación
- Nutritional Studies and Diet · Agriculture Sustainability and Environmental Impact · Consumer Attitudes and Food Labeling
- Palabras clave
- Medicine, Red meat, Confounding, Observational study, Cancer, CINAHL, Cohort study, Internal medicine, Psychological intervention, Pathology
- MeSH
- humans, neoplasms, cardiovascular diseases, diet, meat products, red meat
20 autores
- Robin W.M. Vernooij🇨🇦🇳🇱Dalhousie University; Netherlands Comprehensive Cancer Organisation
- Dena Zeraatkar🇨🇦McMaster University
- Mi Ah Han🇰🇷Chosun University
- Regina El Dib🇨🇦Dalhousie University
- Max Zworth🇨🇦McMaster University
- Kirolos Milio🇨🇦McMaster University
- Daegan Sit🇨🇦University of British Columbia
- Yung Lee🇨🇦McMaster University
- Huda A. Gomaa🇪🇬Alexandria University
- Claudia Valli🇪🇸Iberoamerican Cochrane Centre
- Mateusz Jan Świerz🇵🇱Jagiellonian University
- Yaping Chang🇨🇦McMaster University
- Steven Hanna🇨🇦McMaster University
- Paula M. Brauer🇨🇦University of Guelph
- John L. Sievenpiper🇨🇦St. Michael's Hospital; University of Toronto
- Russell J. de Souza🇨🇦McMaster University
- Pablo Alonso‐Coello🇺🇸🇪🇸Biomedical Research Institute; Iberoamerican Cochrane Centre; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
- Małgorzata Maria Bała🇵🇱Jagiellonian University
- Gordon Henry Guyatt🇨🇦McMaster University
- Bradley C. Johnston🇨🇦Dalhousie University; McMaster University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This article has been corrected. The original version (PDF) is appended to this article as a Supplement.
Background
Studying dietary patterns may provide insights into the potential effects of red and processed meat on health outcomes.
Purpose
To evaluate the effect of dietary patterns, including different amounts of red or processed meat, on all-cause mortality, cardiometabolic outcomes, and cancer incidence and mortality.
Data sources
Systematic search of MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, CINAHL, Web of Science, and ProQuest Dissertations & Theses Global from inception to April 2019 with no restrictions on year or language.
Study selection
Teams of 2 reviewers independently screened search results and included prospective cohort studies with 1000 or more participants that reported on the association between dietary patterns and health outcomes.
Data extraction
Two reviewers independently extracted data, assessed risk of bias, and evaluated the certainty of evidence using GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria.
Data synthesis
Eligible studies that followed patients for 2 to 34 years revealed low- to very-low-certainty evidence that dietary patterns lower in red and processed meat intake result in very small or possibly small decreases in all-cause mortality, cancer mortality and incidence, cardiovascular mortality, nonfatal coronary heart disease, fatal and nonfatal myocardial infarction, and type 2 diabetes. For all-cause, cancer, and cardiovascular mortality and incidence of some types of cancer, the total sample included more than 400 000 patients; for other outcomes, total samples included 4000 to more than 300 000 patients.
Limitation
Observational studies are prone to residual confounding, and these studies provide low- or very-low-certainty evidence according to the GRADE criteria.
Conclusion
Low- or very-low-certainty evidence suggests that dietary patterns with less red and processed meat intake may result in very small reductions in adverse cardiometabolic and cancer outcomes.
Primary funding source
None. (PROSPERO: CRD42017074074).
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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