Dietary Fiber, Whole Grains, and Head and Neck Cancer Prognosis: Findings from a Prospective Cohort Study
Maino Vieytes CA, Mondul AM, Li Z, Zarins KR, Wolf GT, Rozek LS, Arthur AE
Nutrients · 15 citas
Etiquetas de revisión
Sin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- U.S. Department of Agriculture
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute of Food and Agriculture
- Gobierno
- National Cancer Institute
- Gobierno
- National Institute for Occupational Safety and Health
- Gobierno
- NCI NIH HHS
- Gobierno
- NIOSH CDC HHS
- Subvenciones
- National Cancer Institute (P50 CA-097248); National Institute for Occupational Safety and Health (T42-OH008455)); U.S. Department of Agriculture (1011487); National Institute of Food and Agriculture (1011487)
Según 7 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2019-09-27 · Nutrients · vol. 11 · número 10 · pág. 2304
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 18 citas · más que el 85% de estudios similares · 1.7× el promedio de su campo
- Referencias
- 45 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Head and Neck Cancer Studies · Nutrition and Health in Aging · Folate and B Vitamins Research
- Palabras clave
- Medicine, Head and neck cancer, Hazard ratio, Prospective cohort study, Proportional hazards model, Internal medicine, Whole grains, Cohort, Cohort study, Confidence interval, Cancer, Oncology, Food science
- MeSH
- humans, head and neck neoplasms, neoplasm recurrence, local, prognosis, diet, diet surveys, proportional hazards models, risk factors, prospective studies, dietary fiber, aged, middle aged, female, male, whole grains
7 autores
- Christian A. Maino Vieytes🇺🇸University of Illinois Urbana-Champaign
- Alison M. Mondul🇺🇸University of Michigan
- Zonggui Li🇺🇸University of Illinois Urbana-Champaign
- Katie R. Zarins🇺🇸University of Michigan
- Gregory T. Wolf🇺🇸University of Michigan
- Laura S. Rozek🇺🇸University of Michigan
- Anna E. Arthur🇺🇸 · autor de correspondenciaCarle Foundation Hospital; University of Illinois Urbana-Champaign
Resumen
El texto original del estudio, en el idioma en que se publicó.
No studies, to date, have examined the relationship between dietary fiber and recurrence or survival after head and neck cancer diagnosis. The aim of this study was to determine whether pretreatment intake of dietary fiber or whole grains predicted recurrence and survival outcomes in newly diagnosed head and neck cancer (HNC) patients. This was a prospective cohort study of 463 participants baring a new head and neck cancer diagnosis who were recruited into the study prior to the initiation of any cancer therapy. Baseline (pre-treatment) dietary and clinical data were measured upon entry into the study cohort. Clinical outcomes were ascertained at annual medical reviews. Cox proportional hazard models were fit to examine the relationships between dietary fiber and whole grain intakes with recurrence and survival. There were 112 recurrence events, 121 deaths, and 77 cancer-related deaths during the study period. Pretreatment dietary fiber intake was inversely associated with risk of all-cause mortality (hazard ratio (HR): 0.37, 95% confidence interval (CI): 0.14-0.95, ptrend = 0.04). No statistically significant associations between whole grains and prognostic outcomes were found. We conclude that higher dietary fiber intake, prior to the initiation of treatment, may prolong survival time, in those with a new HNC diagnosis.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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