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Ensayo controlado aleatorizado2019Financiado por la industriaVínculos de autores con la industriaAlimentación controladaAcceso abierto

Financiado en parte por Almond Board of California, The Almond Board of California, USDA Project

Prospective randomized controlled pilot study on the effects of almond consumption on skin lipids and wrinkles

Foolad N, Vaughn AR, Rybak I, Burney WA, Chodur GM, Newman JW, Steinberg FM, Sivamani RK

Phytotherapy research : PTR · 21 citas

Etiquetas de revisión

Vínculos de autores con la industriaAlimentación controladaFinanciado por la industria

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
Comida provista por los investigadores

Quién lo pagó

Financiación
Financiado por la industria
Gobierno
U.S. Department of Agriculture
Grupo de la industria
Almond Board of California
Grupo de la industria
The Almond Board of California, USDA Project
Autores
Al menos un autor declara un vínculo económico con la industria
Subvenciones
U.S. Department of Agriculture (2032-51530-022); U.S. Department of Agriculture (2032‐51530‐022‐00D)

Según 3 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2019-10-01 · Phytother Res · vol. 33 · número 12 · págs. 3212–3217
Editorial
Wiley
Citado
35 citas · más que el 89% de estudios similares · 2.6× el promedio de su campo
Referencias
25 trabajos
Acceso
Acceso abierto (revista híbrida) · CC-BY
Áreas de investigación
Nuts composition and effects · Skin Protection and Aging · Phytochemicals and Antioxidant Activities
Palabras clave
almond consumption, dietary supplementation, skin aging, wrinkles, transepidermal water loss, skin barrier function, postmenopausal women, anti-aging, fatty acids, antioxidants
MeSH
humans, lipids, case-control studies, prospective studies, pilot projects, skin aging, aged, aged, 80 and over, middle aged, female, male, prunus dulcis

8 autores

  • Negar Foolad🇺🇸University of California, Davis
  • Alexandra R. Vaughn🇺🇸Drexel University; University of California, Davis
  • Iryna Rybak🇺🇸University of California, Davis
  • Waqas A. Burney🇺🇸University of California, Davis
  • Gwen Chodur🇺🇸University of California, Davis
  • John W. I. Newman🇺🇸Agricultural Research Service; United States Department of Agriculture; Western Human Nutrition Research Center; University of California, Davis
  • Francene M. Steinberg🇺🇸University of California, Davis
  • Raja K. Sivamani🇺🇸 · autor de correspondenciaCalifornia State University, Sacramento; University of California, Davis

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective

Almonds are a rich source of fatty acids and antioxidants, and their supplementation is known to significantly modulate serum lipids. The effects of almond on the skin's lipid barrier and the appearance of wrinkles have not yet been elucidated. The aim of this study was to investigate the effects of almond consumption on facial sebum production and wrinkles.

Methods

This was a prospective, investigator-blinded, randomized controlled trial in which subjects consumed 20% of their daily energy consumption in either almonds or a calorie-matched snack for 16 weeks. This study was completed at the UC Davis Dermatology clinic. Participants were a volunteer sample of generally healthy postmenopausal females with Fitzpatrick skin types 1 and 2. A facial photograph and image analysis system was used to obtain standardized photographs and information on wrinkle width and severity at 0, 8, and 16 weeks. Measurements of transepidermal water loss and sebum production were also completed at 0, 8, and 16 weeks.

Results

Fifty healthy postmenopausal females were recruited, 31 participants were enrolled, and 28 completed the study. Under photographic analysis, the almond group had significantly decreased wrinkle severity and width compared with the control group at 16 weeks (p < .02). Changes in skin barrier function were nonsignificant, measured by the transepidermal water loss (p = .65) between the almond and control groups relative to baseline after 16 weeks. No adverse effects were reported.

Conclusion

Our study demonstrates that daily almond consumption may reduce wrinkle severity in postmenopausal females to potentially have natural antiaging benefits.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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