The Effectiveness of Intermittent Fasting to Reduce Body Mass Index and Glucose Metabolism: A Systematic Review and Meta-Analysis
Cho Y, Hong N, Kim KW, Kim KW, Cho SJ, Lee M, Lee YH, Lee YH, Kang ES, Cha BS, Lee BW
Journal of clinical medicine · 150 citas
Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Inha University
- Universidad u hospital
- Inha University Hospital
- Universidad u hospital
- INHA UNIVERSITY HOSPITAL
Según 3 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2019-10-09 · J Clin Med · vol. 8 · número 10 · pág. 1645
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 206 citas · más que el 94% de estudios similares · 3.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 42 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Diet, Metabolism, and Disease
- Palabras clave
- Medicine, Body mass index, Glycemic, Population, Adiponectin, Internal medicine, Randomized controlled trial, Insulin resistance, Carbohydrate metabolism, Diabetes mellitus, Meta-analysis, Endocrinology, Insulin
10 autores
- Yongin Cho🇰🇷Inha University; Yonsei University
- Namki Hong🇰🇷Yonsei University
- Kyungwon Kim🇰🇷Yonsei University
- Sung June Cho🇰🇷Yonsei University
- Minyoung Lee🇰🇷Yonsei University
- Yeon-hee Lee🇰🇷Yonsei University
- Yong‐ho Lee🇰🇷Yonsei University
- Eun Seok Kang🇰🇷Yonsei University
- Bong Soo🇰🇷Yonsei University
- Byung‐Wan Lee🇰🇷 · autor de correspondenciaYonsei University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The effects of an intermittent fasting diet (IFD) in the general population are still controversial. In this study, we aimed to systematically evaluate the effectiveness of an IFD to reduce body mass index and glucose metabolism in the general population without diabetes mellitus. Cochrane, PubMed, and Embase databases were searched to identify randomized controlled trials and controlled clinical trials that compared an IFD with a regular diet or a continuous calorie restriction diet. The effectiveness of an IFD was estimated by the weighted mean difference (WMD) for several variables associated with glucometabolic parameters including body mass index (BMI) and fasting glucose. The pooled mean differences of outcomes were calculated using a random effects model. From 2814 studies identified through a literature search, we finally selected 12 articles (545 participants). Compared with a control diet, an IFD was associated with a significant decline in BMI (WMD, -0.75 kg/m2; 95% CI, -1.44 to -0.06), fasting glucose level (WMD, -4.16 mg/dL; 95% CI, -6.92 to -1.40), and homeostatic model assessment of insulin resistance (WMD, -0.54; 95% CI, -1.05 to -0.03). Fat mass (WMD, -0.98 kg; 95% CI, -2.32 to 0.36) tended to decrease in the IFD group with a significant increase in adiponectin (WMD, 1008.9 ng/mL; 95% CI, 140.5 to 1877.3) and a decrease in leptin (WMD, -0.51 ng/mL; 95% CI, -0.77 to -0.24) levels. An IFD may provide a significant metabolic benefit by improving glycemic control, insulin resistance, and adipokine concentration with a reduction of BMI in adults.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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