Comparative effects of different types of tree nut consumption on blood lipids: a network meta-analysis of clinical trials
Liu K, Hui S, Wang B, Kaliannan K, Guo X, Liang L
The American journal of clinical nutrition · 38 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Subvenciones
- National Natural Science Foundation of China (81773410)
Según 1 financiador declarado.
Publicación
- Publicado
- 2019-10-19 · Am J Clin Nutr · vol. 111 · número 1 · págs. 219–227
- Editorial
- Elsevier BV
- Citado
- 53 citas · más que el 70% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 56 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Fatty Acid Research and Health
- Palabras clave
- tree nuts, pistachio, Juglans regia, almond, hazelnut, Anacardium occidentale, serum lipids, LDL cholesterol, total cholesterol, triglycerides, HDL cholesterol, cardiovascular risk
- MeSH
- humans, anacardium, pistacia, corylus, juglans, nuts, triglycerides, adult, cholesterol, ldl, cholesterol, hdl, randomized controlled trials as topic, prunus dulcis
6 autores
- Kai Liu🇨🇳Army Medical University; Shenyang Center for Disease Control and Prevention; General Hospital of Shenyang Military Region
- Suocheng Hui🇨🇳Army Medical University
- Bin Wang🇨🇳Army Medical University
- Kanakaraju Kaliannan🇺🇸Harvard University; Massachusetts General Hospital
- Xiaozhong Guo🇨🇳 · autor de correspondenciaGeneral Hospital of Shenyang Military Region
- Linlang Liang🇨🇳 · autor de correspondenciaGeneral Hospital of Shenyang Military Region
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Recent evidence has confirmed that nuts are one of the best food groups at reducing LDL cholesterol and total cholesterol (TC). However, the comparative effects of different types of nuts on blood lipids are unclear.
Objectives
This network meta-analysis of randomized clinical trials aimed to assess the comparative effects of walnuts, pistachios, hazelnuts, cashews, and almonds on typical lipid profiles.
Methods
We conducted literature searches to identify studies comparing ≥2 of the following diets-walnut-enriched, pistachio-enriched, hazelnut-enriched, cashew-enriched, almond-enriched, and control diets-for the management of triglycerides (TGs), LDL cholesterol, TC, and HDL cholesterol. Random-effects network meta-analyses, ranking analyses based on the surface under the cumulative ranking (SUCRA) curves, and sensitivity analyses according to the potential sources of heterogeneity across the included studies were performed for each outcome.
Results
Thirty-four trials enrolling 1677 participants were included in this study. The pistachio-enriched diet was ranked best for TG (SUCRA: 85%), LDL cholesterol (SUCRA: 87%), and TC (SUCRA: 96%) reductions. For TG and TC reductions, the walnut-enriched diet was ranked as the second-best diet. Regarding LDL cholesterol reduction, the almond-enriched diet was ranked second best. The pistachio-enriched and walnut-enriched diets were more effective at lowering TG, LDL cholesterol, and TC compared with the control diet. Regarding TG and TC reductions, the pistachio-enriched diet was also more effective than the hazelnut-enriched diet. For TG reduction, the walnut-enriched diet was better than the hazelnut-enriched diet. However, these findings are limited by the low quality of evidence ratings. In addition, the quality of this network meta-analysis was limited by the small number and generally poor reporting of available studies.
Conclusions
The pistachio-enriched and walnut-enriched diet could be better alternatives for lowering TGs, LDL cholesterol, and TC compared with other nut-enriched diets included in this study. The findings warrant further evaluation by more high-quality studies.This network meta-analysis was registered at www.crd.york.ac.uk/PROSPERO as CRD42019131128.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.