Threshold-Effect Association of Dietary Cholesterol Intake with Dyslipidemia in Chinese Adults: Results from the China Health and Nutrition Survey in 2015
Huang Q, Jiang H, Zhang B, Wang H, Jia X, Huang F, Wang L, Wang Z
Nutrients · 22 citas
Etiquetas de revisión
Sin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Gobierno
- the National Institute for Nutrition and Health, China Center for Disease Control and Prevention; Carolina Population Center
- Gobierno
- NICHD NIH HHS
- Gobierno
- the Ministry of Finance of the People's Republic of China, the China Nutritional Transition Cohort Study
- Gobierno
- the Fogarty International Center, National Institutes of Health
- Gobierno
- NIH HHS
- Subvenciones
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD030880); National Institutes of Health (R24 HD‐050924); National Institutes of Health (R01- HD38700); National Institutes of Health (R01 HD30880); National Institutes of Health (DK-056350); National Institutes of Health (R01-HD30880, DK056350, R24 HD050924, R01-HD38700)
Según 7 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2019-11-27 · Nutrients · vol. 11 · número 12 · pág. 2885
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 29 citas · más que el 91% de estudios similares · 2.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 36 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Lipoproteins and Cardiovascular Health · Cancer, Lipids, and Metabolism · Diabetes, Cardiovascular Risks, and Lipoproteins
- Palabras clave
- Dyslipidemia, Medicine, Hypertriglyceridemia, Cholesterol, Internal medicine, National Health and Nutrition Examination Survey, Hypocholesterolemia, Clinical nutrition, Endocrinology, Triglyceride, Obesity, Environmental health, Population
- MeSH
- humans, hypercholesterolemia, hypertriglyceridemia, cholesterol, dietary, nutrition surveys, odds ratio, adolescent, adult, middle aged, diet records, china, dyslipidemias, cholesterol, ldl, cholesterol, hdl, young adult, asian people
8 autores
- Qiumin Huang🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Hongru Jiang🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Bing Zhang🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Huijun Wang🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Xiaofang Jia🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Feifei Huang🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Liusen Wang🇨🇳Chinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
- Zhihong Wang🇨🇳 · autor de correspondenciaChinese Center For Disease Control and Prevention; National Institute for Nutrition and Health
Resumen
El texto original del estudio, en el idioma en que se publicó.
The association of dietary cholesterol intake with dyslipidemia and subtypes is controversial. This study aimed to examine the association of dietary cholesterol intake with dyslipidemia and subtypes in Chinese adults. Using data from the China Health and Nutrition Survey (CHNS) in 2015, the present study selected 4383 participants aged 18-59 years who were free of diabetes, apoplexy, and myocardial infarction disease. Information was obtained on dietary intake, anthropometric measurements, and blood laboratory measurements. Dietary cholesterol intake was calculated based on the data collected by consecutive 3 days 24 h recalls combined with the weighing of household seasonings and categorized by 11 levels: The first 10 levels in ranges of 50 mg/day and the 11th level at ≥500 mg/day. Dyslipidemia, hypercholesterolemia, hypertriglyceridemia, low-density lipoprotein (LDL)-hypercholesterolemia, and high-density lipoprotein (HDL)-hypocholesterolemia were defined based on the Chinese adult dyslipidemia prevention guide (2016 edition). Multivariable logistic regressions were performed to examine the association of dietary cholesterol intake levels with dyslipidemia and subtypes. The prevalence of dyslipidemia was 37.5% among Chinese adults in 2015 (hypercholesterolemia 9.6%, HDL-hypocholesterolemia 21.1%, LDL-hypercholesterolemia 12.7%, and hypertriglyceridemia 15.2%). The lowest prevalence of hypercholesterolemia and LDL-hypercholesterolemia was 6.7% and 9.4%, respectively, which was relative to a dietary cholesterol intake level of 100.0 to <150.0 mg/day. After adjusting for all potential confounders, adults with the highest dietary cholesterol intake level of ≥500 mg/day compared with the dietary cholesterol intake of 100.0 to <150.0 mg/day showed one-time higher odds of hypercholesterolemia (odds ratios (OR) 2.0, 95% confidence intervals (CI) 1.3-3.3), as well as LDL-hypercholesterolemia (OR 2.0, 95% CI 1.3-3.0), but a null association of dietary cholesterol intake with dyslipidemia, hypertriglyceridemia, and HDL-hypocholesterolemia. The study suggested that a dietary cholesterol intake level of 500 mg/day and above may be a threshold point for high odds of hypercholesterolemia and LDL-hypercholesterolemia.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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