Effects of a healthy diet enriched or not with pecan nuts or extra-virgin olive oil on the lipid profile of patients with stable coronary artery disease: a randomised clinical trial
Campos VP, Portal VL, Markoski MM, Quadros AS, Bersch-Ferreira ÂC, Garavaglia J, Marcadenti A
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 25 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Gobierno
- Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
- Subvenciones
- Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (CHAMADA FAPERGS/MS/CNPq/SESRS n. 002/2013); Conselho Nacional de Desenvolvimento Científico e Tecnológico (487146/2013‐1)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2019-12-19 · J Hum Nutr Diet · vol. 33 · número 3 · págs. 439–450
- Editorial
- Wiley
- Citado
- 34 citas · más que el 90% de estudios similares · 2.8× el promedio de su campo
- Referencias
- 48 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Lipoproteins and Cardiovascular Health
- Palabras clave
- pecan nuts, extra virgin olive oil, stable coronary artery disease, lipid profile, LDL cholesterol, HDL cholesterol, non-HDL cholesterol, TC/HDL-C ratio, healthy eating, dietary supplementation, statin therapy
- MeSH
- humans, carya, lipids, triglycerides, treatment outcome, dietary supplements, adult, aged, aged, 80 and over, middle aged, female, male, cholesterol, ldl, cholesterol, hdl, coronary artery disease, intention to treat analysis, olive oil, diet, healthy
7 autores
- Viviane Paiva de Campos🇧🇷Fundação Universitária de Cardiologia
- Vera Lúcia Portal🇧🇷Fundação Universitária de Cardiologia
- Melissa Medeiros Markoski🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Alexandre Schaan de Quadros🇧🇷Fundação Universitária de Cardiologia
- Ângela Cristine Bersch-Ferreira
- Juliano Garavaglia🇧🇷Universidade Federal de Ciências da Saúde de Porto Alegre
- Aline Marcadenti🇧🇷 · autor de correspondenciaUniversidade Federal de Ciências da Saúde de Porto Alegre; Fundação Universitária de Cardiologia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The present study aimed to assess the effect of a healthy diet, enriched or not with pecan nuts or extra-virgin olive oil, on the lipid profile of patients with stable coronary artery disease (CAD).
Methods
This was a randomised clinical trial conducted for 12 weeks with patients aged between 40 and 80 years with stable CAD for more than 60 days. Individuals were randomised into groups [control group (CG) with 67 patients, pecan nut group (PNG) with 68 patients and olive oil group (OOG) with 69 patients]. The CG was prescribed a healthy diet according to the nutritional guidelines; the PNG was prescribed the same healthy diet plus 30 g day-1 of pecan nuts; and the OOG was prescribed a healthy diet plus 30 mL day-1 of extra-virgin olive oil.
Results
In total, 204 subjects were submitted to an intention-to-treat analysis. After adjustment for baseline values and type of statin used, there was no difference regarding low-density lipoprotein (LDL)-cholesterol (primary outcome), high-density lipoprotein (HDL)-cholesterol, LDL-cholesterol/HDL-cholesterol ratio and HDL-cholesterol/triglycerides ratio according to groups. However, the PNG exhibited a significant reduction in non-HDL-cholesterol levels [PNG: 114.9 (31) mg dL-1 ; CG: 127 (33.6) mg dL-1 ; OOG: 126.6 (37.4) mg dL-1 ; P = 0.033] and in the total cholesterol/HDL-cholesterol ratio [PNG: 3.7 (0.7); CG: 4.0 (0.8); OOG: 4.0 (0.8); P = 0.044] compared to the CG and OOG.
Conclusions
Supplementing a healthy diet with 30 g day-1 of pecan nuts for 12 weeks did not improve LDL-cholesterol levels but may improve other lipid profile markers in patients with stable CAD.
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