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Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis

Wang W, Li J, Chen X, Yu M, Pan Q, Guo L

BMC cardiovascular disorders · 34 citas

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Subvenciones
National Natural Science Foundation of China (81670763); National Natural Science Foundation of China (81471050)

Según 1 financiador declarado y la declaración de financiación del texto completo.

Publicación

Publicado
2020-02-18 · BMC Cardiovasc Disord · vol. 20 · número 1 · pág. 82
Editorial
BioMed Central
Citado
53 citas · más que el 74% de estudios similares · 1.2× el promedio de su campo
Referencias
64 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Food composition and properties · Celiac Disease Research and Management · Nutritional Studies and Diet
Palabras clave
Medicine, Overweight, Waist, Body mass index, Internal medicine, Blood pressure, Obesity, Meta-analysis, Refined grains, Confidence interval, Insulin resistance, Whole grains
MeSH
humans, cardiovascular diseases, obesity, weight loss, c-reactive protein, treatment outcome, risk assessment, risk factors, risk reduction behavior, nutritive value, adult, middle aged, female, male, adiposity, protective factors, biomarkers, whole grains, diet, healthy

6 autores

  • Weihao Wang🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College
  • Jianan Li🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College
  • Xiaoxi Chen🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College
  • Miao Yu🇨🇳Chinese Academy of Medical Sciences & Peking Union Medical College
  • Qi Pan🇨🇳 · autor de correspondenciaChinese Academy of Medical Sciences & Peking Union Medical College
  • Lixin Guo🇨🇳 · autor de correspondenciaChinese Academy of Medical Sciences & Peking Union Medical College

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

The effects of whole grain diet on cardiovascular risks in obese and overweight adults is not well established. Our goal was to conduct a systematic review and meta-analysis on the effect of whole grain diet on cardiovascular risks in obese/overweight adults.

Methods

PubMed, Embase and Cochrane were systematically scanned for randomized controlled trials (RCTs), and studies were selected based on certain inclusion and exclusion criteria. The primary outcome was the effectiveness of whole grain food consumption in reducing body weight. The secondary outcomes were the effect of whole grain food consumption on cardiovascular disease (CVD) risk factors including plasma low-density lipoprotein cholesterol (LDL-C), insulin resistance index, blood pressure, body mass index (BMI), C-reactive protein (CRP), and waist circumference in obese/overweight adults.

Results

Our results showed that whole grain consumption was associated with lower body weight (mean difference (MD) = - 0.5, 95% confidence intervals (CI) [- 0.74, 0.25], I2 = 35%, P 2 = 69%, P 2 = 27%, P = 0.05), waist circumference (MD = -0.12, 95% CI [- 0.92, 0.68], I2 = 44%, P = 0.76), systolic blood pressure (MD = -0.11, 95% CI [- 1.55, 1.33], I2 = 3%, P = 0.88), diastolic blood pressure (MD = -0.44, 95% CI [- 1.44, 0.57], I2 = 15%, P = 0.39), and fasting glucose (MD = -0.05, 95% CI [- 0.12, 0.01], I2 = 31%, P = 0.11) between the two groups.

Conclusion

This study suggests that whole grain food consumption can slightly reduce body weight and CRP in obese/overweight population.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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