Changes in Nut Consumption and Subsequent Cardiovascular Disease Risk Among US Men and Women: 3 Large Prospective Cohort Studies
Liu X, Guasch-Ferré M, Drouin-Chartier JP, Tobias DK, Bhupathiraju SN, Rexrode KM, Willett WC, Sun Q, Li Y
Journal of the American Heart Association · 25 citas
Etiquetas de revisión
Vínculos de autores con la industriaCuestionario de frecuencia de consumoFinanciado por la industriaSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiado por la industria
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Cancer Institute
- Gobierno
- National Institute of Diabetes and Digestive and Kidney Diseases
- Gobierno
- NIDDK NIH HHS
- Gobierno
- NCI NIH HHS
- Gobierno
- NHLBI NIH HHS
- Autores
- Al menos un autor declara un vínculo económico con la industria
- Subvenciones
- National Cancer Institute (U01 CA167552); National Heart, Lung, and Blood Institute (U01 HL145386); National Heart, Lung, and Blood Institute (R01-HL034594); National Cancer Institute (UM1 CA186107); National Heart, Lung, and Blood Institute (R01 HL035464); National Heart, Lung, and Blood Institute (R01-HL-088521); National Cancer Institute (U01 CA176726); National Cancer Institute (UM1-CA-167552); National Institute of Diabetes and Digestive and Kidney Diseases (R01DK120870); National Cancer Institute (UM1 CA176726)
Según 6 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-04-01 · J Am Heart Assoc · vol. 9 · número 7 · pág. e013877
- Editorial
- Wiley
- Citado
- 39 citas · más que el 92% de estudios similares · 3.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 48 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC-ND
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Antioxidant Activity and Oxidative Stress
- Palabras clave
- Medicine, Relative risk, Confidence interval, Prospective cohort study, Lower risk, Proportional hazards model, Stroke (engine), Cohort study, Internal medicine, Nut, Nurses' Health Study
- MeSH
- humans, nuts, cardiovascular diseases, prognosis, incidence, risk assessment, prospective studies, feeding behavior, risk reduction behavior, sex factors, primary prevention, nutritive value, time factors, adult, aged, middle aged, united states, female, male, protective factors, diet, healthy, heart disease risk factors
9 autores
- Xiaoran Liu🇺🇸Harvard University
- Marta Liu Guasch-Ferré🇺🇸Brigham and Women's Hospital; Harvard University
- Jean‐Philippe Drouin‐Chartier🇺🇸Harvard University
- Deirdre Kay Tobias🇺🇸Brigham and Women's Hospital; Harvard University
- Shilpa N Bhupathiraju🇺🇸Brigham and Women's Hospital; Harvard University
- Kathryn M. Rexrode🇺🇸Brigham and Women's Hospital; Harvard University
- Walter Churchill Willett🇺🇸Brigham and Women's Hospital; Harvard University
- Qi Sun🇺🇸Brigham and Women's Hospital; Harvard University
- Yanping Li🇺🇸Harvard University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background We aim to evaluate the association of within-individual changes in consumption of total and specific types of nuts and the subsequent risk of incident cardiovascular disease (CVD) in US men and women. Methods and Results We included 34 103 men from the HPFS (Health Professionals Follow-Up Study) (1986-2012), 77 815 women from the NHS (Nurses' Health Study) (1986-2012), and 80 737 women from the NHS II (1991-2013). We assessed nut consumption every 4 years using validated food frequency questionnaires. We used multivariable Cox proportional hazards regression models to examine the association between 4-year changes in nut consumption and risk of confirmed CVD end points in the subsequent 4 years. Per 0.5 serving/day increase in total nut consumption was associated with lower risk of CVD (relative risk [RR], 0.92; 95% CI, 0.86-0.98), coronary heart disease (RR, 0.94; 95% CI, 0.89-0.99), and stroke (RR, 0.89; 95% CI, 0.83-0.95). Compared with individuals who remained nonconsumers in a 4-year interval, those who had higher consumption of total nuts (≥0.5 servings/day) had a lower risk of CVD (RR, 0.75; 95% CI, 0.67-0.84), coronary heart disease (RR, 0.80; 95% CI, 0.69-0.93), and stroke (RR, 0.68; 95% CI, 0.57-0.82) in next 4 years. Individuals who decreased nut consumption by ≥0.50 servings/day had a higher risk of developing CVD (RR, 1.14; 95% CI, 0.99-1.32), coronary heart disease (RR, 1.06; 95% CI, 0.88-1.28), and stroke (RR, 1.28; 95% CI, 1.02-1.60) when compared with those who maintained their nut consumption. Conclusions Increasing total consumption of nuts and intake of individual types of nuts (eg, walnuts, other tree nuts, and peanuts) was associated with a subsequent lower risk of CVD. These data support the role of nut intake in the primary prevention of CVD. Registration URL: http://www.clinicaltrials.gov. Unique identifiers: NCT00005152 and NCT00005182.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-ND).
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