Financiado en parte por International Nut and Dried Fruit Council
Effect of walnut consumption on markers of blood glucose control: a systematic review and meta-analysis
Neale EP, Guan V, Tapsell LC, Probst YC
The British journal of nutrition · 29 citas
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- International Nut and Dried Fruit Council
Según 1 financiador declarado.
Publicación
- Publicado
- 2020-04-21 · Br J Nutr · vol. 124 · número 7 · págs. 641–653
- Editorial
- Cambridge University Press
- Citado
- 37 citas · más que el 72% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 74 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Natural Antidiabetic Agents Studies
- Palabras clave
- walnut consumption, glycemic control, fasting blood glucose, insulin, HbA1c, insulin resistance, type 2 diabetes, cardiovascular risk, nut intake
- MeSH
- humans, juglans, nuts, diabetes mellitus, type 2, insulin resistance, insulin, blood glucose, eating, randomized controlled trials as topic, biomarkers, glycated hemoglobin
4 autores
- Elizabeth Phillipa Neale🇦🇺 · autor de correspondenciaUniversity of Wollongong; Illawarra Health and Medical Research Institute
- Vivienne X. Guan🇦🇺University of Wollongong; Illawarra Health and Medical Research Institute
- Linda C Tapsell🇦🇺University of Wollongong; Illawarra Health and Medical Research Institute
- Yasmine Probst🇦🇺University of Wollongong; Illawarra Health and Medical Research Institute
Resumen
El texto original del estudio, en el idioma en que se publicó.
Type 2 diabetes mellitus is a chronic disease increasing in global prevalence. Although habitual consumption of walnuts is associated with reduced risk of CVD, there is inconsistent evidence for the impact of walnut consumption on markers of glycaemic control. This systematic review and meta-analysis aimed to examine the effect of walnut consumption on markers of blood glucose control. A systematic search of Medline, PubMed, CINAHL and Cochrane databases (to 2 March 2019) was conducted. Inclusion criteria were randomised controlled trials conducted with adults which assessed the effect of walnut consumption on fasting blood glucose and insulin, glycated Hb and homeostatic model assessment of insulin resistance. Random effects meta-analyses were conducted to assess the weighted mean differences (WMD) for each outcome. Risk of bias in studies was assessed using the Cochrane Risk of Bias tool 2.0. Sixteen studies providing eighteen effect sizes were included in the review. Consumption of walnuts did not result in significant changes in fasting blood glucose levels (WMD: 0·331 mg/dl; 95 % CI -0·817, 1·479) or other outcome measures. Studies were determined to have either 'some concerns' or be at 'high risk' of bias. There was no evidence of an effect of walnut consumption on markers of blood glucose control. These findings suggest that the known favourable effects of walnut intake on CVD are not mediated via improvements in glycaemic control. Given the high risk of bias observed in the current evidence base, there is a need for further high-quality randomised controlled trials.
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