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Ensayo controlado aleatorizado2020Financiado por la industriaVínculos de autores con la industriaAcceso abierto

Financiado en parte por Almond Board of California

Daily almond consumption in cardiovascular disease prevention via LDL-C change in the U.S. population: a cost-effectiveness analysis

Wang J, Lee Bravatti MA, Johnson EJ, Raman G

BMC public health · 6 citas

Etiquetas de revisión

Vínculos de autores con la industriaFinanciado por la industria

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiado por la industria
Gobierno
U.S. Department of Agriculture
Grupo de la industria
Almond Board of California
Autores
Al menos un autor declara un vínculo económico con la industria
Subvenciones
U.S. Department of Agriculture (58-1950-4-003)

Según 2 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2020-04-25 · BMC Public Health · vol. 20 · número 1 · pág. 558
Editorial
BioMed Central
Citado
17 citas · más que el 81% de estudios similares · 1.4× el promedio de su campo
Referencias
41 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Nuts composition and effects · Health Systems, Economic Evaluations, Quality of Life · Nutritional Studies and Diet
Palabras clave
almond consumption, cardiovascular disease prevention, LDL cholesterol, cost-effectiveness, nut intake, acute myocardial infarction, stroke, quality-adjusted life years, net monetary benefit, dietary intervention
MeSH
humans, cardiovascular diseases, diet, adult, cost-benefit analysis, health expenditures, united states, female, male, cholesterol, ldl, prunus dulcis

4 autores

  • Jifan Wang🇺🇸 · autor de correspondenciaTufts University
  • Michelle A. Lee Bravatti🇺🇸Tufts University
  • Elizabeth J. Johnson🇺🇸Tufts University
  • Gowri Raman🇺🇸Tufts Medical Center

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Heart disease is the leading cause of death in the United States. The U.S. Food and Drug Administration approved the health claim that 1.5 oz (42.5 g) of nut intake may reduce the risk of cardiovascular disease. Previous studies have focused on the cost-effectiveness of other foods or dietary factors on primary cardiovascular disease prevention, yet not in almond consumption. This study aimed to examine the cost-effectiveness of almond consumption in cardiovascular disease primary prevention.

Perspective & setting

This study assessed the cost-effectiveness of consuming 42.5 g of almond from the U.S. healthcare sector perspective.

Methods

A decision model was developed for 42.5 g of almond per day versus no almond consumption and cardiovascular disease in the U.S.

Population

Parameters in the model were derived from the literature, which included the probabilities of increasing low-density lipoprotein cholesterol, developing acute myocardial infarction and stroke, treating acute myocardial infarction, dying from the disease and surgery, as well as the costs of the disease and procedures in the U.S. population, and the quality-adjusted life years. The cost of almonds was based on the current price in the U.S. market. Sensitivity analyses were conducted for different levels of willingness-to-pay, the probabilistic sensitivity analysis, ten-year risk prevention, different costs of procedures and almond prices, and patients with or without cardiovascular disease.

Results

The almond strategy had $363 lower cost and 0.02 higher quality-adjusted life years gain compared to the non-almond strategy in the base-case model. The annual net monetary benefit of almond consumption was $1421 higher per person than no almond consumption, when the willingness to pay threshold was set at $50,000 for annual health care expenditure. Almond was more cost-effective than non-almond in cardiovascular disease prevention in all the sensitivity analyses.

Conclusion

Consuming 42.5 g of almonds per day is a cost-effective approach to prevent cardiovascular disease in the short term and potentially in the long term.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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