Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults
Nakamura Y, Watanabe H, Tanaka A, Yasui M, Nishihira J, Murayama N
Nutrients · 32 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Japan Society for the Promotion of Science
- Subvenciones
- Japan Society for the Promotion of Science (18H02606)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-04-23 · Nutrients · vol. 12 · número 4 · pág. 1191
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 60 citas · más que el 93% de estudios similares · 3.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 35 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Diet and metabolism studies · Thermoregulation and physiological responses · Dietary Effects on Health
- Palabras clave
- Bedtime, Medicine, Blood pressure, Body water, Vasopressin, Renal function, Internal medicine, Urine specific gravity, Urine, Blood urea nitrogen, Endocrinology, Animal science, Physiology, Body weight, Biology
- MeSH
- kidney, body water, humans, blood urea nitrogen, glomerular filtration rate, body temperature, blood pressure, drinking, aged, middle aged, female, male, nutritional physiological phenomena, healthy volunteers, biomarkers, gastrointestinal microbiome, organism hydration status, asian people
6 autores
- Yumi Nakamura🇯🇵 · autor de correspondenciaSuntory Foundation for Life Sciences; Suntory Global Innovation Center Ltd. (Japan)
- Hiroshi Watanabe🇯🇵Suntory Foundation for Life Sciences; Suntory Global Innovation Center Ltd. (Japan)
- Aiko Tanaka🇯🇵Hokkaido Information University
- Masato Yasui🇯🇵Keio University Hospital
- Jun Nishihira🇯🇵Hokkaido Information University
- Norihito Murayama🇯🇵Suntory Foundation for Life Sciences; Suntory Global Innovation Center Ltd. (Japan)
Resumen
El texto original del estudio, en el idioma en que se publicó.
Increased hydration is recommended as healthy habit with several merits. However, supportive data are sparse. To assess the efficacy of increased daily water intake, we tested the effect of water supplementation on biomarkers in blood, urine, and saliva. Twenty-four healthy Japanese men and 31 healthy Japanese women with fasting blood glucose levels ranging from 90-125 mg/dL were included. An open-label, two-arm, randomized controlled trial was conducted for 12 weeks. Two additional 550 mL bottles of water on top of habitual fluid intake were consumed in the intervention group. The subjects drank one bottle of water (550 mL) within 2 h of waking, and one bottle (550 mL) 2 h before bedtime. Subjects increased mean fluid intake from 1.3 L/day to 2.0 L/day, without changes in total energy intake. Total body water rate increased with associated water supplementation. There were no significant changes in fasting blood glucose and arginine vasopressin levels, but systolic blood pressure was significantly decreased in the intervention group. Furthermore, water supplementation increased body temperature, reduced blood urea nitrogen concentration, and suppressed estimated glomerular filtration rate reduction. Additionally, existence of an intestinal microbiome correlated with decreased systolic blood pressure and increased body temperature. Habitual water supplementation after waking up and before bedtime in healthy subjects with slightly elevated fasting blood glucose levels is not effective in lowering these levels. However, it represents a safe and promising intervention with the potential for lowering blood pressure, increasing body temperature, diluting blood waste materials, and protecting kidney function. Thus, increasing daily water intake could provide several health benefits.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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