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Metaanálisis2020Acceso abierto

Beneficial Effects of Time-Restricted Eating on Metabolic Diseases: A Systemic Review and Meta-Analysis

Moon S, Kang J, Kim SH, Chung HS, Kim YJ, Yu JM, Cho ST, Oh CM, Kim T

Nutrients · 180 citas

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Universidad u hospital
Gwangju Institute of Science and Technology
Gobierno
National Research Foundation of Korea
Subvenciones
National Research Foundation of Korea (2018R1A2B0002804); National Research Foundation of Korea (2016R1A6A3A04010466)

Según 2 financiadores declarados.

Publicación

Publicado
2020-04-29 · Nutrients · vol. 12 · número 5 · pág. 1267
Editorial
Multidisciplinary Digital Publishing Institute
Citado
233 citas · más que el 99% de estudios similares · 14.6× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
63 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Dietary Effects on Health · Circadian rhythm and melatonin · Diet and metabolism studies
Palabras clave
Circadian rhythm, Medicine, Overweight, Internal medicine, Metabolic syndrome, Confidence interval, Glucose homeostasis, Endocrinology, Blood pressure, Meta-analysis, Obesity, Cochrane Library, Physiology, Cholesterol, Energy homeostasis, Gastroenterology, Insulin resistance
MeSH
humans, metabolic diseases, obesity, body weight, cholesterol, diet therapy, fasting, body composition, circadian rhythm, homeostasis, blood pressure, eating, time, overweight

9 autores

  • Shinje Moon🇰🇷Hallym University
  • Jiseung Kang🇰🇷Gwangju Institute of Science and Technology
  • Sang Hyun Kim🇰🇷Gwangju Institute of Science and Technology
  • Hye Soo Chung🇰🇷Hallym University
  • Yoon Jung Kim🇰🇷Hallym University
  • Jae Myung Yu🇰🇷Hallym University
  • Sung Tae Cho🇰🇷Hallym University
  • Chang‐Myung Oh🇰🇷 · autor de correspondenciaGwangju Institute of Science and Technology
  • Tae Kim🇰🇷 · autor de correspondenciaGwangju Institute of Science and Technology

Resumen

El texto original del estudio, en el idioma en que se publicó.

Various behavioral and physiological pathways follow a pre-determined, 24 hour cycle known as the circadian rhythm. Metabolic homeostasis is regulated by the circadian rhythm. Time-restricted eating (TRE) is a type of intermittent fasting based on the circadian rhythm. In this study, we aim to analyze systemically the effects of TRE on body weight, body composition, and other metabolic parameters. We reviewed articles from PubMed, EMBASE, and the Cochrane Library to identify clinical trials that compared TRE to a regular diet. We included 19 studies for meta-analysis. Participants following TRE showed significantly reduced body weight (mean difference (MD), -0.90; 95% confidence interval (CI): -1.71 to -0.10) and fat mass (MD: -1.58, 95% CI: -2.64 to -0.51), while preserving fat-free mass (MD, -0.24; 95% CI: -1.15 to 0.67). TRE also showed beneficial effects on cardiometabolic parameters such as blood pressure (systolic BP, MD, -3.07; 95% CI: -5.76 to -0.37), fasting glucose concentration (MD, -2.96; 95% CI, -5.60 to -0.33), and cholesterol profiles (triglycerides, MD: -11.60, 95% CI: -23.30 to -0.27). In conclusion, TRE is a promising therapeutic strategy for controlling weight and improving metabolic dysfunctions in those who are overweight or obese. Further large-scale clinical trials are needed to confirm these findings and the usefulness of TRE.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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