A Systematic Review and Meta-Analysis of the Effects of Low-Level Laser Therapy in the Treatment of Diabetic Foot Ulcers
Santos CMD, Rocha RBD, Hazime FA, Cardoso VS
The international journal of lower extremity wounds · 32 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2020-05-12 · Int J Low Extrem Wounds · vol. 20 · número 3 · págs. 198–207
- Editorial
- SAGE Publishing
- Citado
- 52 citas · más que el 69% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 40 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Diabetic Foot Ulcer Assessment and Management · Wound Healing and Treatments
- Palabras clave
- low-level laser therapy, diabetic foot ulcer, wound healing, ulcer size reduction, laser parameters, 632.8 nm, irradiation time, treatment efficacy, safety
- MeSH
- humans, diabetic foot, treatment outcome, wound healing, low-level light therapy
4 autores
- Cristiana Maria dos Santos🇧🇷Universidade Federal do Piauí
- Rebeca Barbosa da Rocha🇧🇷Universidade Federal do Piauí
- Fuad Ahmad Hazime🇧🇷Universidade Federal do Piauí
- Vinícius Saura Cardoso🇧🇷 · autor de correspondenciaUniversidade Federal do Piauí
Resumen
El texto original del estudio, en el idioma en que se publicó.
Diabetic foot ulcers (DFUs) are considered one of the most aggressive and expensive complications of diabetes. Low-level laser therapy (LLLT) has been highlighted as a potential modality of treatment to accelerate the healing of ulcers. This systematic review and meta-analysis aimed to investigate the efficacy of LLLT in the treatment of DFU and identify the LLLT application parameters recommended for the treatment of DFU over the past 10 years. A systematic search was conducted in PubMed, BVS, PEDro, Scopus, Web of Science, and CINAHL up to March 31, 2019. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines, randomized controlled trials (RCTs) that assessed the effect of LLLT on the treatment of DFU were included. Thirteen RCTs with a total of 361 participants were included in this review. Three RCTs reported a reduction in the percentage size of the ulcers and were included in the meta-analysis. The meta-analysis of the percentage size difference demonstrated a significant reduction in ulcer size in the LLLT group compared with controls (22.96 [95% confidence interval = 18.22-27.69; z = 9.51, P 2, 3 to 6 J/cm2, and irradiation for 30 to 80 seconds, 3 times weekly for a month is of benefit to patients with DFU. LLLT is effective and safe for the treatment of DFU. Additionally, well-designed, high-quality studies are needed to allow its ideal parameterization for clinical practice.
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