Traditional Brazilian Diet and Olive Oil Reduce Cardiometabolic Risk Factors in Severely Obese Individuals: A Randomized Trial
Santos ASEAC, Rodrigues APDS, Rosa LPS, Noll M, Silveira EA
Nutrients · 24 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-05-14 · Nutrients · vol. 12 · número 5 · pág. 1413
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 27 citas · más que el 93% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Edible Oils Quality and Analysis · Fatty Acid Research and Health
- Palabras clave
- extra virgin olive oil, morbid obesity, cardiometabolic risk factors, LDL cholesterol, HDL cholesterol, TC/HDL-C ratio, LDL/HDL ratio, homocysteine, triglycerides, dietary intervention
- MeSH
- humans, obesity, morbid, triglycerides, body mass index, treatment outcome, diet, eating, adolescent, adult, aged, middle aged, brazil, female, male, cholesterol, ldl, cholesterol, hdl, young adult, olive oil, cardiometabolic risk factors
5 autores
- Annelisa Silva e Alves de Carvalho Santos🇧🇷 · autor de correspondenciaUniversidade Federal de Goiás
- Ana Paula dos Santos Rodrigues🇧🇷Universidade Federal de Goiás
- Lorena Pereira de Souza Rosa🇧🇷Universidade Federal de Goiás
- Mark A. Noll🇧🇷Instituto Federal Goiano; Universidade Federal de Goiás
- Érika Aparecida Silveira🇧🇷 · autor de correspondenciaUniversidade Federal de Goiás
Resumen
El texto original del estudio, en el idioma en que se publicó.
Cardioprotective effects associated with extra virgin olive oil (EVOO) have been studied within the Mediterranean diet. However, little is known about its consumption in the traditional Brazilian diet (DieTBra) or without any dietary prescription, particularly in severely obese individuals. This study aimed to assess the effectiveness of DieTBra and EVOO in cardiometabolic risk factor (CMRF) reduction in severely obese individuals. We conducted a parallel randomized clinical trial with 149 severely obese individuals (body mass index ≥ 35.0 kg/m2) aged 18-65 years, assigned to three groups: 52 mL/day of EVOO (n = 50), DieTBra (n = 49), and DieTBra + 52 mL/day of EVOO (n = 50). Participants were followed up for 12 weeks. Low-density lipoprotein cholesterol (LDL-c) was the primary endpoint and several cardiometabolic parameters were secondary endpoints. Endpoints were compared at baseline and at the end of the study using analysis of variance, the Kruskal-Wallis test, and Student's t-test. The TC/High-density lipoprotein (HDL) ratio (-0.33 ± 0.68, p = 0.002) and LDL/HDL ratio (-0.26 ± 0.59, p = 0.005) decreased in the EVOO group. Delta values for all variables showed no significant statistical difference between groups. However, we highlight the clinical significance of LDL-c reduction in the EVOO group by 5.11 ± 21.79 mg/dL and in the DieTBra group by 4.27 ± 23.84 mg/dL. We also found a mean reduction of around 10% for Castelli II (LDL/HDL) and homocysteine in the EVOO group and TG and the TG/HDL ratio in the DieTBra group. EVOO or DieTBra when administered alone lead to reduction in some cardiometabolic risk parameters in severely obese individuals.
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