Financiado en parte por Meat and Livestock Australia, Be Fit Foods, Eli Lilly Australia
The effect of ultra-processed very low-energy diets on gut microbiota and metabolic outcomes in individuals with obesity: A systematic literature review
Lane M, Howland G, West M, Hockey M, Marx W, Loughman A, O'Hely M, Jacka F, Rocks T
Obesity research & clinical practice · 35 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Organización sin fines de lucro
- Wilson Foundation
- Organización sin fines de lucro
- Geelong Region Medical Research Foundation
- Organización sin fines de lucro
- Australian Rotary Health
- Organización sin fines de lucro
- Ian Potter Foundation
- Grupo de la industria
- Meat and Livestock Australia
- Universidad u hospital
- Deakin University
- Universidad u hospital
- University of Melbourne
- Gobierno
- State Government of Victoria
- Organización sin fines de lucro
- Fernwood Foundation
- Empresa
- Be Fit Foods
- Empresa
- Eli Lilly Australia
- Gobierno
- National Health and Medical Research Council
- Universidad u hospital
- Brain and Behaviour Research Institute, University of Wollongong
- Subvenciones
- University of Melbourne (1108125); National Health and Medical Research Council (1147970); National Health and Medical Research Council (1147980)
Según 13 financiadores declarados.
Publicación
- Publicado
- 2020-05-01 · Obes Res Clin Pract · vol. 14 · número 3 · págs. 197–204
- Editorial
- Elsevier BV
- Citado
- 50 citas · más que el 63% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 95 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY
- Áreas de investigación
- Gut microbiota and health · Diet and metabolism studies · Bariatric Surgery and Outcomes
- Palabras clave
- ultra-processed foods, very low calorie diet, obesity, gut microbiota, metabolic outcomes, lifestyle intervention, Firmicutes, Bacteroidetes, Faecalibacterium prausnitzii, Roseburia, Lachnospiraceae, Bifidobacteriaceae, Alistipes, Bacteroides
- MeSH
- humans, obesity, treatment outcome, caloric restriction, prospective studies, cross-over studies, food handling, adult, female, male, randomized controlled trials as topic, non-randomized controlled trials as topic, gastrointestinal microbiome, obesity management
9 autores
- Melissa M. Lane🇦🇺 · autor de correspondenciaDeakin University
- Gina Howland🇦🇺Deakin University
- Madeline L. West🇦🇺Deakin University
- Meghan Hockey🇦🇺Deakin University
- Wolfgang Marx🇦🇺Deakin University
- Amy Loughman🇦🇺Deakin University
- Martin O’Hely🇦🇺Deakin University; Murdoch Children's Research Institute
- Felice N. Jacka🇦🇺Deakin University
- Tetyana Rocks🇦🇺Deakin University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This systematic review investigated the effects of ultra-processed very low-energy diets on gut microbiota and metabolic outcomes in individuals with obesity. MEDLINE complete, EMBASE, Scopus, Cochrane and CINAHL were searched between date of inception and October 2019. Seven trials were reviewed (a total of 130 participants, with 10 to 44 participants in each trial). Of these, five were single-arm interventions and included very low-energy diets adjunctive to comprehensive lifestyle interventions such as nutritional counselling, behavioural therapy and exercise programmes. Changes to taxa within the Firmicutes phylum were found, including reduced abundance of potentially beneficial butyrogenic microbes (Roseburia, Faecalbacterium prausnitzii, Lactobacillus, Bifidobacterium and Lachnospiraeceae). Conversely, increased abundance of potentially pathogenic or opportunistic microbes from the Bacteroidetes phylum was reported, including increases in Alistipes and Bacteroides taxa. However, outcomes were inconsistent, with some trials also showing decreases in Bacteroides taxa and increases in commensal microbiota, such as Lachnospiraceae and Bifidobacteriaceae. The changes in metabolic parameters observed from baseline to after the ultra-processed very low-energy diets were mostly beneficial or were not significantly altered. Although the selected articles were deemed to have satisfactory methodological quality, to understand the possible direct effects of these regimens on gut microbiota, further rigorously designed trials, with more standardised microbiological sequencing techniques and detailed reporting, are required. Study registration: Prospero ID: CRD42019124436.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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