Association between Egg Consumption and Cholesterol Concentration: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Li MY, Chen JH, Chen C, Kang YN
Nutrients · 30 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Taipei Medical University
- Universidad u hospital
- Wan Fang Hospital
- Subvenciones
- Taipei Medical University (108-wf-eva-01)
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-07-04 · Nutrients · vol. 12 · número 7 · pág. 1995
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 32 citas · más que el 63% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 63 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Nutrition, Genetics, and Disease
- Palabras clave
- Confidence interval, Meta-analysis, Randomized controlled trial, Cholesterol, Medicine, Internal medicine, Subgroup analysis, Lipoprotein, High-density lipoprotein, Endocrinology, Gastroenterology, Animal science, Biology
- MeSH
- humans, diet, diet surveys, eating, eggs, adolescent, adult, aged, middle aged, female, male, cholesterol, ldl, cholesterol, hdl, randomized controlled trials as topic, young adult
4 autores
- Man-Yun Li🇹🇼Taipei Medical University
- Jinhua Chen🇹🇼Wan Fang Hospital; Taipei Medical University
- Chiehfeng Chen🇹🇼 · autor de correspondenciaWan Fang Hospital; Taipei Medical University
- Yi‐No Kang🇹🇼 · autor de correspondenciaNational Taiwan University; Wan Fang Hospital; Taipei Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The association of egg consumption and serum cholesterol concentrations in healthy people has been discussed for a long time. In this study, we aimed to explore association of egg consumption with on low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c) concentrations and the LDL-c/HDL-c ratio through meta-analysis. This systematic review only included randomized controlled trials (RCTs) investigating egg consumption in healthy populations without combination therapy. We extracted mean and standard deviation for LDL-c/HDL-c ratio, LDL-c/HDL-c. The extracted data were pooled in a random-effects model and were presented as mean difference (MD) with 95% confidence interval (CI). Moreover, subgroup analyses were conducted for understanding effects of more egg consumption (MEC) on different intervention periods, egg-consumption levels, classification of responders. Overall, 17 RCTs met the eligibility criteria and pooled results showed MEC group had a higher LDL-c/HDL-c ratio than the control group (MD = 0.14, p = 0.001, I2 = 25%). The MEC group also had higher LDL-c than the control group (MD = 8.14, p 2 = 18%). Moreover, for the subset of intervention over two months, the MEC group seemed to have a larger effect size than the subset of intervention within two months. This synthesis, the largest meta-analysis on this topic, shows the impact of egg consumption on lipid profiles among healthy subjects. Notably, longer time with MEC may lead to higher LDL-c/HDL-c ratio and LDL-c. However, RCTs with long tern follow-up are needed to guarantee the association between egg consumption and human health.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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