Association Between Egg Consumption and Risk of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis
Krittanawong C, Narasimhan B, Wang Z, Virk HUH, Farrell AM, Zhang H, Tang WHW
The American journal of medicine · 32 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2020-07-09 · Am J Med · vol. 134 · número 1 · págs. 76–83.e2
- Editorial
- Elsevier BV
- Citado
- 56 citas · más que el 87% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 38 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Cardiovascular Health and Risk Factors · Lipoproteins and Cardiovascular Health
- Palabras clave
- egg consumption, cardiovascular risk, coronary artery disease, dietary cholesterol, dietary fat, cardiovascular outcomes
- MeSH
- humans, cardiovascular diseases, risk factors, feeding behavior, eggs
7 autores
- Chayakrit Krittanawong🇺🇸 · autor de correspondenciaMichael E. DeBakey VA Medical Center; Baylor College of Medicine; Icahn School of Medicine at Mount Sinai
- Bharat Narasimhan🇺🇸Icahn School of Medicine at Mount Sinai
- Zhen Wang🇺🇸Mayo Clinic
- Hafeez Ul Hassan Virk🇺🇸Case Western Reserve University
- Ann M. Farrell🇺🇸Mayo Clinic
- HongJu Zhang🇺🇸Mayo Clinic
- W.H. Wilson Tang🇺🇸Cleveland Clinic
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Considerable controversy remains on the relationship between egg consumption and cardiovascular disease risk. The objective of this systematic review and meta-analysis was to explore the association between egg consumption and overall cardiovascular disease events.
Methods
We systematically searched Ovid MEDLINE, Ovid Embase, Ovid Cochrane Database of Systematic Reviews, Scopus, and Web of Science from database inception in 1966 through January 2020 for observational studies that reported the association between egg consumption and cardiovascular disease events. Two investigators independently reviewed data. Conflicts were resolved through consensus. Random-effects meta-analyses were used. Sources of heterogeneity were analyzed.
Results
We identified 23 prospective studies with a median follow-up of 12.28 years. A total of 1,415,839 individuals with a total of 123,660 cases and 157,324 cardiovascular disease events were included. Compared with the consumption of no or 1 egg/day, higher egg consumption (more than 1 egg/day) was not associated with significantly increased risk of overall cardiovascular disease events (pooled hazard ratios, 0.99; 95% confidence interval, 0.93-1.06; P < .001; I² = 72.1%). Higher egg consumption (more than 1 egg/day) was associated with a significantly decreased risk of coronary artery disease (pooled hazard ratios, 0.89; 95% confidence interval, 0.86-0.93; P < .001; I² = 0%), compared with consumption of no or 1 egg/day.
Conclusions
Our analysis suggests that higher consumption of eggs (more than 1 egg/day) was not associated with increased risk of cardiovascular disease, but was associated with a significant reduction in risk of coronary artery disease.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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