Effects of time-restricted feeding on body weight, body composition and vital signs in low-income women with obesity: A 12-month randomized clinical trial
de Oliveira Maranhão Pureza IR, da Silva Junior AE, Silva Praxedes DR, Lessa Vasconcelos LG, de Lima Macena M, Vieira de Melo IS, de Menezes Toledo Florêncio TM, Bueno NB
Clinical nutrition (Edinburgh, Scotland) · 73 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Gobierno
- Fundação de Amparo à Pesquisa do Estado do Amazonas
- Subvenciones
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (1793050); Fundação de Amparo à Pesquisa do Estado do Amazonas (14/2016)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2020-07-13 · Clin Nutr · vol. 40 · número 3 · págs. 759–766
- Editorial
- Elsevier BV
- Citado
- 97 citas · más que el 98% de estudios similares · 6.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 45 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Obesity, Physical Activity, Diet
- Palabras clave
- time-restricted feeding, obesity, low-income women, hypocaloric diet, caloric restriction, body weight, body composition, body fat percentage, waist circumference, vital signs, blood pressure, heart rate, body temperature, long-term weight loss, physical activity, resting metabolic rate, dietary energy level, food insecurity, food assistance programs
- MeSH
- humans, obesity, body weight, body temperature, caloric restriction, fasting, body composition, blood pressure, heart rate, poverty, adult, female, waist circumference, vital signs
8 autores
- Isabele Rejane de Oliveira Maranhão Pureza🇧🇷Universidade Federal de Alagoas
- André Eduardo da Silva Júnior🇧🇷Universidade Federal de Alagoas
- Dafiny Rodrigues Silva Praxedes🇧🇷Universidade Federal de Alagoas
- Laís Gomes Lessa Vasconcelos🇧🇷Universidade Federal de Alagoas
- Mateus de Lima Macêna🇧🇷Universidade Federal de Alagoas
- Ingrid Sofia Vieira de Melo🇧🇷Instituto Federal de Educação, Ciência e Tecnologia de Alagoas
- Telma Maria de Menezes Toledo Florêncio🇧🇷Universidade Federal de Alagoas
- Nassib Bezerra Bueno🇧🇷 · autor de correspondenciaUniversidade Federal de Alagoas
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background & aims
Time-restricted feeding (TRF) studies usually are of short-term, involving heterogeneous populations, without a control group with similar energy restriction. Besides, it seldom assess vital signs such as body temperature and heart rate, which may be influenced by the fasting state. In this investigation, we assessed the long-term effects of TRF on body weight, body composition and vital signs of low-income women with obesity undergoing diets with the same energy deficit.
Methods
Low-income women with obesity were randomly allocated to a group with a hypoenergetic diet and 12 h of TRF or to a group with only a hypoenergetic diet, for 12 months. Body fat and waist circumference were estimated using a tetrapolar electrical bioimpedance and an inelastic measuring tape, respectively, at baseline and after 4, 6 and 12 months of intervention. Systolic and diastolic blood pressure, heart rate, and axillary temperature were measured at baseline and 12 months of intervention. The energy content of the diets was determined based on the women's resting metabolic rate (by indirect calorimetry) and level of physical activity (by triaxial accelerometers). Effects were analyzed using an intention-to-treat approach.
Results
Fifty-eight women were randomized and 31 (53.44%) were lost to follow-up at 12 months. Dropout rates were similar between groups. In the intention-to-treat analysis, there were no significant changes in the body weight after 12 months (Differences in changes from baseline between groups: -0.05 95%CI [-2.34; 2.24] Kg; p = 0.96). An increase in axillary temperature (0.40 °C, 95% CI [-0.14; 0.67]°C, p < 0.01), a reduction in the percentage of body fat (-1.64%, 95% CI [-3.08; -0.19]%, p = 0.02) and waist circumference (-2.57 cm, 95% CI [-5.73; 0.58] cm, p = 0.03 in the mixed model involving 4 measurements) were observed in the intervention group, when compared to the control group.
Conclusions
TRF showed no effects on weight loss. Nevertheless the findings on waist circumference and body fat, although not clinically meaningful, suggest that this strategy may help in the long-term management of obesity in this population, since it is an easy to apply intervention. Axillary temperature findings warrants further investigation. Registered under www.ensaiosclinicos.gov.br Identifier no. RBR-387v6v.
Trial registration
http://www.ensaiosclinicos.gov.br/rg/RBR-387v6v/.
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