Co-consumption of Vegetables and Fruit, Whole Grains, and Fiber Reduces the Cancer Risk of Red and Processed Meat in a Large Prospective Cohort of Adults from Alberta's Tomorrow Project
Maximova K, Khodayari Moez E, Dabravolskaj J, Ferdinands AR, Dinu I, Lo Siou G, Al Rajabi A, Veugelers PJ
Nutrients · 16 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Alberta Health Services
- Organización sin fines de lucro
- Alberta Cancer Foundation
- Organización sin fines de lucro
- Canadian Cancer Society
- Organización sin fines de lucro
- Partenariat Canadien Contre Le Cancer
- Gobierno
- Health Canada
- Gobierno
- Canadian Institutes of Health Research
- Gobierno
- CIHR
- Subvenciones
- Canadian Institutes of Health Research (151568); Alberta Cancer Foundation (702936); Alberta Cancer Foundation (151568); Canadian Institutes of Health Research (702936); Canadian Cancer Society (702936)
Según 7 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-07-29 · Nutrients · vol. 12 · número 8 · pág. 2265
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 26 citas · más que el 90% de estudios similares · 2.4× el promedio de su campo
- Referencias
- 74 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Cancer Risks and Factors
- Palabras clave
- Red meat, Medicine, Hazard ratio, Prospective cohort study, Incidence (geometry), Confounding, Environmental health, Proportional hazards model, Cohort, Cancer, Population, Cohort study, Refined grains, Cancer prevention, Cancer incidence, Processed meat, Lower risk, Whole grains, Food science, Confidence interval, Internal medicine, Biology
- MeSH
- humans, fruit, vegetables, neoplasms, diet, diet surveys, incidence, risk factors, prospective studies, time factors, dietary fiber, meat products, adult, aged, middle aged, alberta, female, male, whole grains, red meat
8 autores
- Katerina Maximova🇨🇦 · autor de correspondenciaUniversity of Alberta
- Elham Khodayari Moez🇨🇦University of Alberta
- Julia Dabravolskaj🇨🇦University of Alberta
- Alexa Rae Ferdinands🇨🇦University of Alberta
- Irina A Dinu🇨🇦University of Alberta
- Géraldine Lo Siou🇨🇦Alberta Health Services
- Ala Al Rajabi🇦🇪Zayed University
- Paul J. Veugelers🇨🇦University of Alberta
Resumen
El texto original del estudio, en el idioma en que se publicó.
We examined whether co-consumption of red and processed meat with key foods items and food constituents recommended for cancer prevention (vegetables and fruit, whole grains, and fiber) mitigates cancer incidence. In a prospective cohort of 26,218 adults aged 35-69 years at baseline, dietary intake was collected through 124-item past-year food frequency questionnaire. Incidence of all-cause and 15 cancers previously linked to red and processed meat intake was obtained through data linkage with a cancer registry (average follow-up 13.5 years). Competing risk Cox Proportional Hazard models estimated cancer risk and Accelerated Failure Time models estimated time-to-cancer occurrence for different combinations of intake levels while considering mortality from vital statistics and established confounders. Co-consumption of low vegetables and fruit intake with high processed meat was associated with higher incidence of all-cause and 15 cancers (men: HR = 1.85, 1.91; women: HR = 1.44, 1.49) and accelerated time-to-cancer occurrence (men: 6.5 and 7.1 years and women: 5.6 and 6.3 years, respectively), compared to high vegetables and fruit with low processed meat intake. Less pronounced and less consistent associations were observed for whole grains and fiber and for red meat. The findings provide initial evidence toward refining existing cancer prevention recommendations to optimize the intake and combination of foods in the general adult population.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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