Effect of alternate-day fasting on obesity and cardiometabolic risk: A systematic review and meta-analysis
Park J, Seo YG, Paek YJ, Song HJ, Park KH, Noh HM
Metabolism: clinical and experimental · 63 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2020-08-07 · Metabolism · vol. 111 · pág. 154336
- Editorial
- Elsevier BV
- Citado
- 93 citas · más que el 87% de estudios similares · 1.9× el promedio de su campo
- Referencias
- 41 trabajos
- Acceso
- De pago
- Áreas de investigación
- Dietary Effects on Health · Diet and metabolism studies · Obesity, Physical Activity, Diet
- Palabras clave
- alternate-day fasting, obesity, cardiometabolic risk, body mass index, body weight, fat mass, lean body mass, waist circumference, total cholesterol, caloric restriction, time-restricted feeding, weight regain, overweight adults
- MeSH
- heart, humans, cardiovascular diseases, obesity, fasting, adolescent, adult, aged, middle aged, female, male, young adult
6 autores
- Jihyun Park🇰🇷Hallym University Sacred Heart Hospital
- Young‐Gyun Seo🇰🇷 · autor de correspondenciaHallym University Sacred Heart Hospital
- Yu‐Jin Paek🇰🇷Hallym University Sacred Heart Hospital
- Hong Ji Song🇰🇷Hallym University Sacred Heart Hospital
- Kyung‐Hee Park🇰🇷Hallym University Sacred Heart Hospital
- Hye‐Mi Noh🇰🇷Hallym University Sacred Heart Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background & aims
Alternate-day fasting (ADF) is related to weight reduction, lowered risks of weight regain, and relative lean body mass preservation compared to continuous energy restriction. This meta-analysis aimed to assess the effects of ADF on obesity-related factors and cardiometabolic risk factors in adults.
Methods
Using PubMed, EMBASE, and Cochrane online databases, an electronic search was performed. Randomized controlled trials were investigated to evaluate ADF effects on body mass index (BMI), body weight (BW), waist circumference, body fat mass (FM), lean body mass, and cardiometabolic risk factors in adults aged ≥18 years. By utilizing a random-effects model, meta-analyses to assess weighted mean difference (WMD) with 95% confidence intervals (CIs) were performed for eight randomized controlled trials (total participants = 728).
Results
We observed significant effects of ADF for BMI (WMD -0.73 kg/m2, 95% CI -1.13 to -0.34), FM (WMD -1.27 kg, 95% CI -2.09 to -0.46), and total cholesterol (WMD -8.14 mg/dL, 95% CI -14.59 to -1.69). Subgroup analyses indicated that significant intervention effects were observed for BMI, BW, FM, and total cholesterol when compared to the control, the participants were overweight, and the study duration was <6 months. ADF is effective in reducing waist circumference in adults aged ≥40 years with obesity. However, there was no difference between ADF and continuous energy restriction, time-restricted feeding, or control with regard to lean body mass.
Conclusions
Current evidence suggests that ADF effectively lowers BMI, BW, FM, and total cholesterol in adults with overweight within 6 months compared to the control.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.