Olive oil and risk of breast cancer: a systematic review and dose-response meta-analysis of observational studies
Sealy N, Hankinson SE, Houghton SC
The British journal of nutrition · 23 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2020-09-04 · Br J Nutr · vol. 125 · número 10 · págs. 1148–1156
- Editorial
- Cambridge University Press
- Citado
- 32 citas · más que el 75% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nutritional Studies and Diet · Edible Oils Quality and Analysis · Cancer Risks and Factors
- Palabras clave
- olive oil, breast cancer risk, dietary intake, dose-response relationship, monounsaturated fatty acids, polyphenols, women's health
- MeSH
- humans, breast neoplasms, diet, risk factors, dose-response relationship, drug, female, olive oil, observational studies as topic
3 autores
- Naria R. Z. Sealy🇺🇸University of Massachusetts Amherst
- Susan E. Hankinson🇺🇸University of Massachusetts Amherst
- Serena C. Houghton🇺🇸 · autor de correspondenciaUniversity of Massachusetts Amherst
Resumen
El texto original del estudio, en el idioma en que se publicó.
Olive oil consumption has been suggested to be inversely associated with breast cancer risk, probably due to its high MUFA and polyphenol content. The purpose of this meta-analysis was to assess the association between olive oil and breast cancer risk, including assessing the potential for a dose-response association. We performed a systematic search of PubMed, Web of Science, CINAHL and Cochrane Central Register of Controlled Trials through June 2020, identifying ten observational studies (two prospective studies and eight case-control studies) for meta-analysis. We estimated summary OR and 95 % CI for the highest v. lowest olive oil intake category across studies using random effect models and assessed the dose-response relationship between olive oil and breast cancer risk using restricted cubic splines. The summary OR comparing women with the highest intake to those with the lowest category of olive oil intake was 0·48 (95 % CI 0·09, 2·70) in prospective studies and 0·76 (95 % CI 0·54, 1·06) in case-control studies, with evidence of substantial study heterogeneity (prospective I2 = 89 %, case-control I2 = 82 %). There was no significant dose-response relationship for olive oil and breast cancer risk; the OR for a 14 g/d increment was 0·93 (95 % CI 0·83, 1·04). There may be a potential inverse association between olive oil intake and breast cancer; however, since the estimates are non-significant and the certainty level is very low, additional prospective studies with better assessment of olive oil intake are needed.
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