Effects of Total Red Meat Intake on Glycemic Control and Inflammatory Biomarkers: A Meta-Analysis of Randomized Controlled Trials
O'Connor LE, Kim JE, Clark CM, Zhu W, Campbell WW
Advances in nutrition (Bethesda, Md.) · 40 citas
Etiquetas de revisión
Mezcla carne procesada con no procesadaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Purdue University's Bilsland Dissertation Fellowship
Según 1 financiador declarado.
Publicación
- Publicado
- 2020-08-27 · Adv Nutr · vol. 12 · número 1 · págs. 115–127
- Editorial
- Elsevier BV
- Citado
- 53 citas · más que el 75% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 71 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nutritional Studies and Diet · Diet, Metabolism, and Disease · Fatty Acid Research and Health
- Palabras clave
- glycemic control, inflammatory markers, fasting blood glucose, insulin, HOMA-IR, HbA1c, C-reactive protein, cytokines, alternative diets, dose-response relationship, cardiometabolic disease, diabetes risk, dietary intervention, risk of bias, heterogeneity sources, meta-regression, risk of bias assessment, quality of evidence
- MeSH
- humans, diabetes mellitus, type 2, insulin, blood glucose, lactation, randomized controlled trials as topic, biomarkers, red meat, glycemic control
5 autores
- Lauren E O’Connor🇺🇸National Institutes of Health; Purdue University West Lafayette; National Cancer Institute
- Jung Eun Kim🇸🇬🇺🇸National University of Singapore; Purdue University West Lafayette
- Caroline M Clark🇺🇸Purdue University West Lafayette
- Wenbin Zhu🇺🇸Purdue University West Lafayette
- Wayne W. Campbell🇺🇸 · autor de correspondenciaPurdue University West Lafayette
Resumen
El texto original del estudio, en el idioma en que se publicó.
Our objective was to conduct a systematic review and meta-analysis to assess the effects of total red meat (TRM) intake on glycemic control and inflammatory biomarkers using randomized controlled trials of individuals free from cardiometabolic disease. We hypothesized that higher TRM intake would negatively influence glycemic control and inflammation based on positive correlations between TRM and diabetes. We found 24 eligible articles (median duration, 8 weeks) from 1172 articles searched in PubMed, Cochrane, and CINAHL up to August 2019 that included 1) diet periods differing in TRM; 2) participants aged ≥19 years; 3) included either men or women who were not pregnant/lactating; 4) no diagnosed cardiometabolic disease; and 5) data on fasting glucose, insulin, HOMA-IR, glycated hemoglobin (HbA1c), C-reactive protein (CRP), or cytokines. We used 1) a repeated-measures ANOVA to assess pre to post diet period changes; 2) random-effects meta-analyses to compare pre to post changes between diet periods with ≥ vs. 0.2). Risk of bias (85% of studies were fair to good) did not influence results. Total red meat consumption, for up to 16 weeks, does not affect changes in biomarkers of glycemic control or inflammation for adults free of, but at risk for, cardiometabolic disease. This trial was registered at PROSPERO as 2018 CRD42018096031.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.