Effects of baru almond oil (Dipteryx alata Vog.) supplementation on body composition, inflammation, oxidative stress, lipid profile, and plasma fatty acids of hemodialysis patients: A randomized, double-blind, placebo-controlled clinical trial
Schincaglia RM, Cuppari L, Neri HFS, Cintra DE, Sant'Ana MR, Mota JF
Complementary therapies in medicine · 12 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Según 1 financiador declarado.
Publicación
- Publicado
- 2020-06-11 · Complement Ther Med · vol. 52 · pág. 102479
- Editorial
- Elsevier BV
- Citado
- 35 citas · más que el 86% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 61 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Dialysis and Renal Disease Management · Fatty Acid Research and Health
- Palabras clave
- Dipteryx alata, hemodialysis patients, chronic kidney disease, inflammation, C-reactive protein, oxidative stress, body composition, lipid profile, plasma fatty acids
- MeSH
- humans, inflammation, lipids, plant oils, c-reactive protein, capsules, renal dialysis, double-blind method, body composition, oxidative stress, middle aged, female, male, renal insufficiency, chronic
6 autores
- Raquel Machado Schincaglia🇧🇷Universidade Federal de Goiás
- Lílian Cuppari🇧🇷Universidade Federal de São Paulo
- Hiasmin Franciely da Silva Neri🇧🇷Universidade Federal de Goiás
- Dennys E. Cintra🇧🇷Universidade Estadual de Campinas (UNICAMP)
- Marcella Ramos Sant’Ana🇧🇷Universidade Estadual de Campinas (UNICAMP)
- João Felipe Mota🇧🇷 · autor de correspondenciaUniversidade Federal de Goiás
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The consumption of nuts and edible seeds is associated with the improvement of the metabolic profile and reduction of cardiovascular diseases. However, the effects of its subproducts, such as oil, are still poorly studied. This study aimed to evaluate the effect of the baru almond oil supplementation on inflammation, oxidative stress, body composition, lipid profile, and plasma fatty acids of hemodialysis patients.
Methods
In a randomized, double-blind, 12-week placebo-controlled clinical study, hemodialysis patients were supplemented with 5 g of baru oil (BG, n = 17) or 5 g of mineral oil (placebo, BP, n = 12). Body composition, renal function, ultra-sensitive C-reactive protein (us-CRP), oxidative stress, plasma fatty acids, and lipid profile were analysed before and after the intervention.
Results
Patients were aged 50.5 ± 2.2 years and the average time of dialyses was 52,1 ± 42,6 months. The BG decreased us-CRP concentration compared to PG (-1.2 ± 0.2 vs. + 0.8 ± 0.2 mg / L,d = 0.88; p = 0.01). Baru almond oil supplementation was not effective in improving body composition, lipid profile, and oxidative stress.
Conclusion
Baru almond oil supplementation decreased us-CRP concentration in patients with chronic kidney disease under hemodialysis treatment.
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