Egg Consumption and Stroke Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies
Tang H, Cao Y, Yang X, Zhang Y
Frontiers in nutrition · 10 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Health and Family Planning Commission of Sichuan Province
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-09-08 · Front Nutr · vol. 7 · pág. 153
- Editorial
- Frontiers Media
- Citado
- 28 citas · más que el 77% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 42 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Antioxidant Activity and Oxidative Stress · Consumer Attitudes and Food Labeling
- Palabras clave
- Meta-analysis, Relative risk, Medicine, Prospective cohort study, Stroke (engine), Confidence interval, Subgroup analysis, Cochrane Library, Cohort study, Lower risk, Internal medicine
4 autores
- Hui Tang🇨🇳North Sichuan Medical University; Sichuan University; West China Hospital of Sichuan University; Nanchong Central Hospital
- Yi Lin Cao🇨🇳Sichuan University; West China Hospital of Sichuan University
- Xiang Yang🇨🇳Sichuan University; West China Hospital of Sichuan University
- Yuekang Zhang🇨🇳 · autor de correspondenciaSichuan University; West China Hospital of Sichuan University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background: The present study was performed to systematically quantify the association between egg consumption and stroke risk as inconsistent results have been produced. Methods: Three electronic databases (PubMed, Embase, and Cochrane Library), previous reviews, meta-analyses, and bibliographies of relevant articles were retrieved from prospective cohort studies published before July 1, 2020. The random-effects model was employed to estimate summary relative risks (RRs) and 95% confidence intervals (CIs). A dose-response analysis was also performed when data were available. Results: Sixteen publications involving 24 prospective cohort studies were included in our final meta-analysis. No significant association between egg consumption and stroke risk was identified (RR = 0.92, 95% CI: 0.84-1.01) for the highest vs. the lowest quintiles of egg intake. Subgroup analysis indicated that geographic location significantly modified the effect of egg consumption on stroke risk. Higher egg consumption was attributed to a reduced probability of stroke in Asia (RR = 0.83, 95% CI: 0.73-0.94), but not in North America (RR = 0.95, 95% CI: 0.77-1.16) or Europe (RR = 1.02, 95% CI: 0.91-1.16). Dose-response analysis demonstrated a nearly J-shaped curve between egg consumption and risk of stroke. A decreased risk was observed for the intake of one to four eggs weekly and an increased risk for the intake of more than six eggs weekly. The results were significant at an intake of 10 eggs weekly. Conclusions: The evidence from this meta-analysis showed that a J-shaped association exists between egg consumption and stroke risk.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.