Effect of 12 months of creatine supplementation and whole-body resistance training on measures of bone, muscle and strength in older males
Candow DG, Chilibeck PD, Gordon J, Vogt E, Landeryou T, Kaviani M, Paus-Jensen L
Nutrition and health · 24 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Saskatchewan Health Research Foundation
- Gobierno
- Canada Foundation for Innovation
Según 2 financiadores declarados.
Publicación
- Publicado
- 2020-11-24 · Nutr Health · vol. 27 · número 2 · págs. 151–159
- Editorial
- SAGE Publishing
- Citado
- 47 citas · más que el 92% de estudios similares · 2.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 26 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Cardiovascular and exercise physiology · Biochemical effects in animals
- Palabras clave
- Creatine, Placebo, Medicine, Creatine Monohydrate, Lean body mass, Bone mineral, Bone resorption, Bone density, Internal medicine, Osteoporosis, Physical therapy, Body weight
- MeSH
- muscles, muscle, skeletal, humans, creatine, double-blind method, body composition, dietary supplements, aged, male, muscle strength, resistance training
7 autores
- Darren Glenn Candow🇨🇦 · autor de correspondenciaUniversity of Regina
- Philip David Chilibeck🇨🇦University of Saskatchewan
- Julianne J. Gordon🇨🇦University of Saskatchewan
- Emelie Vogt🇨🇦University of Regina
- Tim Landeryou🇨🇦University of Saskatchewan
- Mojtaba Kaviani🇨🇦Acadia University
- Lisa Paus-Jensen🇨🇦University of Saskatchewan
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The combination of creatine supplementation and resistance training (10-12 weeks) has been shown to increase bone mineral content and reduce a urinary indicator of bone resorption in older males compared with placebo. However, the longer-term effects (12 months) of creatine and resistance training on bone mineral density and bone geometric properties in older males is unknown.
Aim
To assess the effects of 12 months of creatine supplementation and supervised, whole-body resistance training on bone mineral density, bone geometric properties, muscle accretion, and strength in older males.
Methods
Participants were randomized to supplement with creatine (n = 18, 49-69 years, 0.1 g·kg-1·d-1) or placebo (n = 20, 49-67 years, 0.1 g·kg-1·d-1) during 12 months of supervised, whole-body resistance training.
Results
After 12 months of training, both groups experienced similar changes in bone mineral density and geometry, bone speed of sound, lean tissue and fat mass, muscle thickness, and muscle strength. There was a trend (p = 0.061) for creatine to increase the section modulus of the narrow part of the femoral neck, an indicator of bone bending strength, compared with placebo. Adverse events did not differ between creatine and placebo.
Conclusions
Twelve months of creatine supplementation and supervised, whole-body resistance training had no greater effect on measures of bone, muscle, or strength in older males compared with placebo.
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