Effects of Omega-3 Fatty Acids on Muscle Mass, Muscle Strength and Muscle Performance among the Elderly: A Meta-Analysis
Huang YH, Chiu WC, Hsu YP, Lo YL, Wang YH
Nutrients · 108 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2020-12-04 · Nutrients · vol. 12 · número 12 · pág. 3739
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 139 citas · más que el 89% de estudios similares · 2.2× el promedio de su campo
- Referencias
- 51 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutrition and Health in Aging · Fatty Acid Research and Health · Muscle metabolism and nutrition
- Palabras clave
- omega-3 fatty acids, dietary supplementation, sarcopenia, muscle mass, muscle strength, muscle performance, older adults, Timed Up and Go test, walking speed
- MeSH
- muscle, skeletal, humans, fatty acids, omega-3, docosahexaenoic acids, eicosapentaenoic acid, gait, diet, dietary supplements, aged, middle aged, female, male, muscle strength, randomized controlled trials as topic, sarcopenia, physical functional performance
5 autores
- Ya-Hui Huang🇹🇼Taipei City Hospital; Taipei Medical University
- Wan‐Chun Chiu🇹🇼Taipei Medical University
- Yuan‐Pin Hsu🇹🇼Wan Fang Hospital; Taipei Medical University
- Yen-Li Lo🇹🇼National Yang Ming University
- Yuan‐Hung Wang🇹🇼 · autor de correspondenciaTaipei Medical University-Shuang Ho Hospital; Taipei Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
There is increasing evidence showing the role of fatty acids and their derived lipid intermediates in the regulation of skeletal muscle mass synthesis and function. However, the role of omega-3 fatty acids remains unclear. Therefore, we conducted a meta-analysis to evaluate the potential effects of omega-3 fatty acids on sarcopenia-related performances among the elderly. Eligible literature and reports of randomized controlled trials were comprehensively searched from the PubMed, Cochrane Library, ClinicalTrials.gov, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases until July 2018. A total of 10 articles were available for the meta-analysis. There were minor benefits for muscle mass gain (0.33 kg; 95% CI: 0.05, 0.62) and timed up and go performance (-0.30 s; 95% CI: -0.43, -0.17). Subgroup analyses regarding muscle mass and walk speed indicated that omega-3 fatty acid supplements at more than 2 g/day may contribute to muscle mass gain (0.67 kg; 95% CI: 0.16, 1.18) and improve walking speed, especially for those receiving more than 6 months of intervention (1.78 m/sec; 95% CI: 1.38, 2.17). Our findings provide some insight into the effects of omega-3 fatty acids on muscle mass, especially for those taking supplements at more than 2 g/day. We also observed that a long period of omega-3 fatty acids supplementation may improve walking speed.
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