Effects of time-restricted feeding in weight loss, metabolic syndrome and cardiovascular risk in obese women
Schroder JD, Falqueto H, Mânica A, Zanini D, de Oliveira T, de Sá CA, Cardoso AM, Manfredi LH
Journal of translational medicine · 107 citas
Cómo se estudió
- Diseño
- Ensayo clínico controlado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Universidade Comunitária da Região de Chapecó
- Universidad u hospital
- Universidade Federal da Fronteira Sul
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Sin clasificar
- UFFS
- Subvenciones
- Universidade Federal da Fronteira Sul (480/GR/UFFS/2018); Universidade Federal da Fronteira Sul (1010/GR/UFFS/2018)
Según 5 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2021-01-06 · J Transl Med · vol. 19 · número 1 · pág. 3
- Editorial
- BioMed Central
- Citado
- 148 citas · más que el 99% de estudios similares · 12.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 53 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Dietary Effects on Health · Enhanced Recovery After Surgery · Circadian rhythm and melatonin
- Palabras clave
- Medicine, Overweight, Metabolic syndrome, Weight loss, Obesity, Waist, Anthropometry, Body mass index, Population, Internal medicine, Type 2 diabetes, Diabetes mellitus, Physiology, Endocrinology, Environmental health
- MeSH
- humans, cardiovascular diseases, diabetes mellitus, type 2, obesity, weight loss, body mass index, risk factors, quality of life, middle aged, female, overweight, metabolic syndrome, heart disease risk factors
8 autores
- Jéssica Daniela Schröder🇧🇷Universidade Federal da Fronteira Sul
- Hugo Falqueto🇧🇷Universidade Federal da Fronteira Sul
- Aline Mânica🇧🇷Community University of Chapecó Region - Unochapecó
- Daniela Zanini🇧🇷Universidade Federal da Fronteira Sul
- Tácio de Oliveira🇧🇷Universidade Federal da Fronteira Sul
- Clodoaldo Antônio De Sá🇧🇷Community University of Chapecó Region - Unochapecó
- Andréia Machado Cardoso🇧🇷Universidade Federal da Fronteira Sul
- Leandro Henrique Manfredi🇧🇷 · autor de correspondenciaUniversidade Federal da Fronteira Sul
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The increasing prevalence of overweight and obesity among the worldwide population has been associated with a range of adverse health consequences such as Type 2 diabetes and cardiovascular diseases. The metabolic syndrome (MetS) is a cluster of cardiometabolic abnormalities that occur more commonly in overweight individuals. Time-restricted feeding (TRF) is a dietary approach used for weight loss and overall health. TRF may be an option for those subjects who struggle with extreme restriction diets with foods that generally do not belong to an individual's habits.
Objective
The purpose of this study was to determine the effect of TRF on body composition and the association of weight loss with metabolic and cardiovascular risks in obese middle-aged women.
Methods
A non-randomized controlled clinical trial was performed over 3 months in obese women (TRF group, n = 20, BMI 32.53 ± 1.13 vs. Control n = 12, BMI 34.55 ± 1.20). The TRF protocol adopted was 16 h without any energy intake followed by 8 h of normal food intake.
Main outcomes and measures
Anthropometric measurements, body composition, blood biomarkers, cardiovascular risk in 30 years (CVDRisk30y), and quality of life were evaluated at baseline and after the 3 months.
Results
TRF was effective in reducing weight (~ 4 kg), BMI, % of body fat (%BF), waist circumference from baseline without changes in blood biomarkers associated with MetS. TRF promoted a reduction in CVDRisk30y (12%) wich was moderately correlated with %BF (r = 0.62, n = 64, p < 0.001) and %MM (r = - 0.74, n = 64, p < 0.001).
Conclusions
TRF protocol reduces body weight without changes in biomarkers related to MetS. In addition, the anthropometric evaluation that predicts %BF and %MM could be used as an approach to follow individuals engaged in the TRF regimen since they correlate with cardiovascular risk.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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