Photobiomodulation therapy is not better than placebo in patients with chronic nonspecific low back pain: a randomised placebo-controlled trial
Guimarães LS, Costa LDCM, Araujo AC, Nascimento DP, Medeiros FC, Avanzi MA, Leal-Junior ECP, Costa LOP, Tomazoni SS
Pain · 22 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2021-01-08 · Pain · vol. 162 · número 6 · págs. 1612–1620
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 32 citas · más que el 92% de estudios similares · 2.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 55 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Musculoskeletal pain and rehabilitation · Pain Management and Treatment
- Palabras clave
- low-level laser therapy, chronic non-specific low back pain, placebo comparison, pain intensity, disability, physiotherapy, musculoskeletal pain
- MeSH
- humans, low back pain, treatment outcome, brazil, chronic pain, low-level light therapy
9 autores
- Layana de Souza Guimarães🇧🇷 · autor de correspondenciaUniversidade Cidade de São Paulo
- Lucíola da Cunha Menezes Costa🇧🇷Universidade Cidade de São Paulo
- Amanda Costa Araújo🇧🇷Universidade Cidade de São Paulo
- Dafne Port Nascimento🇧🇷Universidade Cidade de São Paulo
- Flávia Cordeiro Medeiros🇧🇷Universidade Cidade de São Paulo
- Marina Athayde Avanzi🇧🇷Universidade Cidade de São Paulo
- Ernesto César Pinto Leal‐Junior🇧🇷Universidade Nove de Julho
- Leonardo Oliveira Pena Costa🇧🇷Universidade Cidade de São Paulo
- Shaiane Silva Tomazoni🇧🇷Universidade Cidade de São Paulo
Resumen
El texto original del estudio, en el idioma en que se publicó.
Abstract
Photobiomodulation therapy (PBMT) has been used in several musculoskeletal disorders to reduce pain, inflammation, and promoting tissue regeneration. The current evidence about the effects of PBMT on low back pain (LBP) is still conflicting. We aimed to evaluate the effects of PBMT against placebo on pain intensity and disability in patients with chronic nonspecific LBP. This was a prospectively registered, randomised placebo-controlled trial, with blinded patients, therapists, and assessors. The study was conducted on an outpatient physical therapy clinic in Brazil, between April 2017 and May 2019. A total of 148 patients with chronic nonspecific LBP were randomised to either active PBMT (n = 74) or placebo (n = 74). Patients from both groups received 12 treatment sessions, 3 times a week, for 4 weeks. Patients from both groups also received an educational booklet based on "The Back Book." Clinical outcomes were measured at baseline and at follow-up appointments at 4 weeks, 3, 6, and 12 months after randomisation. The primary outcomes were pain intensity and disability measured at 4 weeks. We estimated the treatment effects using linear mixed models following the principles of intention-to-treat. There was no clinical important between-group differences in terms of pain intensity (mean difference = 0.01 point; 95% confidence interval = -0.94 to 0.96) and disability (mean difference = -0.63 points; 95% confidence interval = -2.23 to 0.97) at 4 weeks. Patients did not report any adverse events. Photobiomodulation therapy was not better than placebo to reduce pain and disability in patients with chronic nonspecific LBP.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.